Challenges of intervention, treatment, and antibiotic resistance of biofilm-forming microorganisms

G Gebreyohannes, A Nyerere, C Bii, DB Sbhatu - Heliyon, 2019 - cell.com
Background Biofilms are multicellular communities of microorganisms held together by a self-
produced extracellular matrix. The ability of microbes to form biofilm is a universal …

Current trends on seaweeds: Looking at chemical composition, phytopharmacology, and cosmetic applications

B Salehi, J Sharifi-Rad, AML Seca, DCGA Pinto… - Molecules, 2019 - mdpi.com
Seaweeds have received huge interest in recent years given their promising potentialities.
Their antioxidant, anti-inflammatory, antitumor, hypolipemic, and anticoagulant effects are …

Quorum quenching: role in nature and applied developments

C Grandclément, M Tannières, S Moréra… - FEMS microbiology …, 2016 - academic.oup.com
Quorum sensing (QS) refers to the capacity of bacteria to monitor their population density
and regulate gene expression accordingly: the QS-regulated processes deal with …

Exploiting quorum sensing to confuse bacterial pathogens

B LaSarre, MJ Federle - Microbiology and molecular biology …, 2013 - journals.asm.org
Cell-cell communication, or quorum sensing, is a widespread phenomenon in bacteria that
is used to coordinate gene expression among local populations. Its use by bacterial …

Quorum sensing inhibitors: an overview

VC Kalia - Biotechnology advances, 2013 - Elsevier
Excessive and indiscriminate use of antibiotics to treat bacterial infections has lead to the
emergence of multiple drug resistant strains. Most infectious diseases are caused by …

Quorum sensing in Gram-negative bacteria: small-molecule modulation of AHL and AI-2 quorum sensing pathways

WRJD Galloway, JT Hodgkinson, SD Bowden… - Chemical …, 2011 - ACS Publications
Numerous species of bacteria employ a mechanism of intercellular communication known
as quorum sensing. This signaling process allows the cells comprising a bacterial colony to …

Antimicrobial resistance, respiratory tract infections and role of biofilms in lung infections in cystic fibrosis patients

O Ciofu, T Tolker-Nielsen, PØ Jensen, H Wang… - Advanced drug delivery …, 2015 - Elsevier
Lung infection is the main cause of morbidity and mortality in patients with cystic fibrosis and
is mainly dominated by Pseudomonas aeruginosa. The biofilm mode of growth makes …

[HTML][HTML] Attenuation of Pseudomonas aeruginosa virulence by quorum sensing inhibitors

M Hentzer, H Wu, JB Andersen, K Riedel… - The EMBO …, 2003 - embopress.org
Traditional treatment of infectious diseases is based on compounds that kill or inhibit growth
of bacteria. A major concern with this approach is the frequent development of resistance to …

Inhibition of quorum sensing in Pseudomonas aeruginosa biofilm bacteria by a halogenated furanone compound

M Hentzer, K Riedel, TB Rasmussen… - …, 2002 - microbiologyresearch.org
Novel molecular tools have been constructed which allow for in situ detection of N-acyl
homoserine lactone (AHL)-mediated quorum sensing in Pseudomonas aeruginosa biofilms …

Chemical interactions between marine macroalgae and bacteria

F Goecke, A Labes, J Wiese, JF Imhoff - Marine ecology progress series, 2010 - int-res.com
We review research from the last 40 yr on macroalgal–bacterial interactions. Marine
macroalgae have been challenged throughout their evolution by microorganisms and have …