Small molecule conformational preferences derived from crystal structure data. A medicinal chemistry focused analysis
Based on torsion angle distributions of frequently occurring substructures, conformation
preferences of druglike molecules are presented, accompanied by a review of the relevant …
preferences of druglike molecules are presented, accompanied by a review of the relevant …
Topology of cyclo-octane energy landscape
Understanding energy landscapes is a major challenge in chemistry and biology. Although
a wide variety of methods have been invented and applied to this problem, very little is …
a wide variety of methods have been invented and applied to this problem, very little is …
Atroposelective synthesis of eight-membered lactam-bridged N-arylindoles via stepwise cut-and-sew strategy
The development of efficient processes for the preparation of structurally diverse axially
chiral biaryls has been an important goal in synthetic organic chemistry and asymmetric …
chiral biaryls has been an important goal in synthetic organic chemistry and asymmetric …
Synthesis and Characterization of Imine-Palladacycles Containing Imidate “Pseudohalide” Ligands: Efficient Suzuki–Miyaura Cross-Coupling Precatalysts and Their Activation To Give Pd0 …
JL Serrano, L Garcia, J Perez, E Perez, J Garcia… - …, 2011 - ACS Publications
Dinuclear palladacyclic complexes [{Pd (C∧ N)(μ-NCO)} 2](C∧ N= N-phenylbenzaldimine,
Phbz) containing asymmetric imidato units (− NCO–= succinimidate (succ; 1), phthalimidate …
Phbz) containing asymmetric imidato units (− NCO–= succinimidate (succ; 1), phthalimidate …
Water-soluble Pd–imidate complexes: broadly applicable catalysts for the synthesis of chemically modified nucleosides via Pd-catalyzed cross-coupling
A broadly applicable catalyst system consisting of water-soluble Pd–imidate complexes has
been enployed for the Suzuki–Miyaura cross-coupling of four different nucleosides in water …
been enployed for the Suzuki–Miyaura cross-coupling of four different nucleosides in water …
N-heterocyclic-carbene complexes readily prepared from di-μ-hydroxopalladacycles catalyze the Suzuki arylation of 9-bromophenanthrene
New cyclometalated palladium complexes of general formula [Pd (Bmim)(X)(C∧ N)] have
been synthesized by a novel reaction route involving di-μ-hydroxo-palladacycles [{Pd (μ …
been synthesized by a novel reaction route involving di-μ-hydroxo-palladacycles [{Pd (μ …
Novel saccharinate-bridged palladium complexes for efficient C–O bond activation displaying promising luminescence properties
MD Santana, R García-Bueno, G García… - Dalton …, 2012 - pubs.rsc.org
The synthesis of mono-and dinuclear cyclometallated palladium (II) complexes with
deprotonated saccharinate ligands displaying different coordination modes is described …
deprotonated saccharinate ligands displaying different coordination modes is described …
Systematic description of molecular deformations with Cremer–Pople puckering and deformation coordinates utilizing analytic derivatives: Applied to cycloheptane …
The conformational properties of ring compounds such as cycloalkanes determine to a large
extent their stability and reactivity. Therefore, the investigation of conformational processes …
extent their stability and reactivity. Therefore, the investigation of conformational processes …
Eight-membered palladacycles derived from the insertion of olefins into the Pd− C bond of ortho-palladated pharmaceuticals phenethylamine and phentermine …
The ortho-metalated complexes derived from phenethylamine and phentermine,[Pd (C, N-
C6H4CH2CR2NH2-2)(μ-X)] 2 (R= H, X= Br (A); R= Me, X= Cl (B)), react with olefins giving …
C6H4CH2CR2NH2-2)(μ-X)] 2 (R= H, X= Br (A); R= Me, X= Cl (B)), react with olefins giving …
Palladium Complexes of Methylene-Bridged P-Stereogenic, Unsymmetrical Diphosphines
Optically pure P-stereogenic methylphosphine–boranes P (BH3) PhArMe (Ar= 1-naphthyl (1-
Np), 9-phenanthryl (1-Phen), 2-biphenylyl (1-Biph)) have been used to prepare six …
Np), 9-phenanthryl (1-Phen), 2-biphenylyl (1-Biph)) have been used to prepare six …