Mitonuclear communication in homeostasis and stress

PM Quirós, A Mottis, J Auwerx - Nature reviews Molecular cell biology, 2016 - nature.com
Mitochondria participate in crucial cellular processes such as energy harvesting and
intermediate metabolism. Although mitochondria possess their own genome—a vestige of …

[HTML][HTML] Mitochondrial dysfunction and mitochondrial dynamics-The cancer connection

S Srinivasan, M Guha, A Kashina… - Biochimica et Biophysica …, 2017 - Elsevier
Mitochondrial dysfunction is a hallmark of many diseases. The retrograde signaling initiated
by dysfunctional mitochondria can bring about global changes in gene expression that alters …

[HTML][HTML] Redox control of senescence and age-related disease

A Chandrasekaran, MPS Idelchik, JA Melendez - Redox biology, 2017 - Elsevier
The signaling networks that drive the aging process, associated functional deterioration, and
pathologies has captured the scientific community's attention for decades. While many …

Nuclear-mitochondrial interactions

BR Walker, CT Moraes - Biomolecules, 2022 - mdpi.com
Mitochondria, the cell's major energy producers, also act as signaling hubs, interacting with
other organelles both directly and indirectly. Despite having its own circular genome, the …

Mitochondrial disorders as windows into an ancient organelle

SB Vafai, VK Mootha - Nature, 2012 - nature.com
Much of our current knowledge about mitochondria has come from studying patients who
have respiratory chain disorders. These disorders comprise a large collection of individually …

Investigating the relationship between brand experience, brand authenticity, brand equity, and customer satisfaction: Evidence from Vietnam

VD Tran, NTT Nguyen - Cogent Business & Management, 2022 - Taylor & Francis
The purpose of this research is to investigate the relationship between brand experience,
brand authenticity, brand equity, and how those factors effect on customer satisfaction. The …

Mitochondrial effectors of cellular senescence: beyond the free radical theory of aging

DV Ziegler, CD Wiley, MC Velarde - Aging cell, 2015 - Wiley Online Library
Cellular senescence is a process that results from a variety of stresses, leading to a state of
irreversible growth arrest. Senescent cells accumulate during aging and have been …

Transcriptional paradigms in mammalian mitochondrial biogenesis and function

RC Scarpulla - Physiological reviews, 2008 - journals.physiology.org
Mitochondria contain their own genetic system and undergo a unique mode of cytoplasmic
inheritance. Each organelle has multiple copies of a covalently closed circular DNA genome …

Cancer as a metabolic disease

TN Seyfried, LM Shelton - Nutrition & metabolism, 2010 - Springer
Emerging evidence indicates that impaired cellular energy metabolism is the defining
characteristic of nearly all cancers regardless of cellular or tissue origin. In contrast to normal …

Mitochondrial signaling: the retrograde response

RA Butow, NG Avadhani - Molecular cell, 2004 - cell.com
Mitochondrial retrograde signaling is a pathway of communication from mitochondria to the
nucleus that influences many cellular and organismal activities under both normal and …