Objective To report the ESICM consensus and clinical practice recommendations on fluid
therapy in neurointensive care patients. Design A consensus committee comprising 22 …

Background Acute treatment of cerebral edema and elevated intracranial pressure is a
common issue in patients with neurological injury. Practical recommendations regarding …

Background Increased intracranial pressure has been shown to be strongly associated with
poor neurological outcomes and mortality for patients with acute traumatic brain injury …

Hyperosmolar therapy is regarded as the mainstay for treatment of elevated intracranial
pressure (ICP) in traumatic brain injury (TBI). This still has been disputed as application of …

Traumatic brain injuries (TBIs) constitute a significant public health issue and a major source
of disability and death in the United States and worldwide. TBIs are strongly associated with …

Objective In neurotrauma care, a better understanding of treatments after traumatic brain
injury (TBI) has led to a significant decrease in morbidity and mortality in this population. TBI …

Acute traumatic brain injury (TBI) is a major cause of mortality and disability worldwide.
Intracranial pressure (ICP)-lowering is a critical management priority in patients with …

Background: Mannitol and hypertonic saline are widely used to treat raised intracranial
pressure (ICP) after traumatic brain injury (TBI), but the clinical superiority of one over the …

Background: Mannitol and hypertonic saline (HTS) are effective in reducing intracranial
pressure (ICP) after severe traumatic brain injury (TBI). However, their efficacy on the ICP …

Abstract Purpose Current Neurocritical Care Society guidelines on the management of
cerebral edema recommend hypertonic saline (HTS) over mannitol in some scenarios, but …