Motor symptoms in Parkinson's disease: A unified framework

AA Moustafa, S Chakravarthy, JR Phillips… - Neuroscience & …, 2016 - Elsevier
Parkinson's disease (PD) is characterized by a range of motor symptoms. Besides the
cardinal symptoms (akinesia and bradykinesia, tremor and rigidity), PD patients show …

Mechanisms of deep brain stimulation

TM Herrington, JJ Cheng… - Journal of …, 2016 - journals.physiology.org
Deep brain stimulation (DBS) is widely used for the treatment of movement disorders
including Parkinson's disease, essential tremor, and dystonia and, to a lesser extent, certain …

[HTML][HTML] Local field potentials in Parkinson's disease: a frequency-based review

Z Yin, G Zhu, B Zhao, Y Bai, Y Jiang… - Neurobiology of …, 2021 - Elsevier
Deep brain stimulation (DBS) surgery offers a unique opportunity to record local field
potentials (LFPs), the electrophysiological population activity of neurons surrounding the …

[HTML][HTML] The pathophysiology of Parkinson's disease tremor

MF Dirkx, M Bologna - Journal of the Neurological Sciences, 2022 - Elsevier
Tremor is one of the primary motor symptoms of Parkinson's disease (PD), and it is
characterized by a highly phenomenological heterogeneity. Clinical and experimental …

A systematic review of local field potential physiomarkers in Parkinson's disease: from clinical correlations to adaptive deep brain stimulation algorithms

BCM van Wijk, RMA de Bie, M Beudel - Journal of neurology, 2023 - Springer
Deep brain stimulation (DBS) treatment has proven effective in suppressing symptoms of
rigidity, bradykinesia, and tremor in Parkinson's disease. Still, patients may suffer from …

[HTML][HTML] The clinical and electrophysiological investigation of tremor

G Deuschl, JS Becktepe, M Dirkx… - Clinical …, 2022 - Elsevier
The various forms of tremor are now classified in two axes: clinical characteristics (axis 1)
and etiology (axis 2). Electrophysiology is an extension of the clinical exam …

Investigation of EEG abnormalities in the early stage of Parkinson's disease

CX Han, J Wang, GS Yi, YQ Che - Cognitive neurodynamics, 2013 - Springer
The objective of the present study was to investigate brain activity abnormalities in the early
stage of Parkinson's disease (PD). To achieve this goal, eyes-closed resting state …

Beta oscillations in the cortico-basal ganglia loop during parkinsonism

E Stein, I Bar-Gad - Experimental Neurology, 2013 - Elsevier
In the normal brain beta band oscillatory activity has been associated with retaining of
ongoing motor activities. In Parkinson's disease, enhanced beta band oscillatory activity is …

[HTML][HTML] Dopaminergic therapy in Parkinson's disease decreases cortical beta band coherence in the resting state and increases cortical beta band power during …

JS George, J Strunk, R Mak-McCully, M Houser… - NeuroImage: Clinical, 2013 - Elsevier
It is not yet well understood how dopaminergic therapy improves cognitive and motor
function in Parkinson's disease (PD). One possibility is that it reduces the pathological …

Neuronal network oscillations in neurodegenerative diseases

V Nimmrich, A Draguhn, N Axmacher - Neuromolecular medicine, 2015 - Springer
Cognitive and behavioral acts go along with highly coordinated spatiotemporal activity
patterns in neuronal networks. Most of these patterns are synchronized by coherent …