Ecological modelling approaches for predicting emergent properties in microbial communities
Recent studies have brought forward the critical role of emergent properties in sha**
microbial communities and the ecosystems of which they are a part. Emergent properties …
microbial communities and the ecosystems of which they are a part. Emergent properties …
Genome-resolved metagenomics: a game changer for microbiome medicine
N Kim, J Ma, W Kim, J Kim, P Belenky… - Experimental & Molecular …, 2024 - nature.com
Recent substantial evidence implicating commensal bacteria in human diseases has given
rise to a new domain in biomedical research: microbiome medicine. This emerging field …
rise to a new domain in biomedical research: microbiome medicine. This emerging field …
Genome-scale metabolic reconstruction of 7,302 human microorganisms for personalized medicine
The human microbiome influences the efficacy and safety of a wide variety of commonly
prescribed drugs. Designing precision medicine approaches that incorporate microbial …
prescribed drugs. Designing precision medicine approaches that incorporate microbial …
In vitro interaction network of a synthetic gut bacterial community
A key challenge in microbiome research is to predict the functionality of microbial
communities based on community membership and (meta)-genomic data. As central …
communities based on community membership and (meta)-genomic data. As central …
A dietary carbohydrate – gut Parasutterella – human fatty acid biosynthesis metabolic axis in obesity and type 2 diabetes
Recent rodent microbiome experiments suggest that besides Akkermansia, Parasutterella
sp. are important in type 2 diabetes and obesity development. In the present translational …
sp. are important in type 2 diabetes and obesity development. In the present translational …
METABOLIC: high-throughput profiling of microbial genomes for functional traits, metabolism, biogeochemistry, and community-scale functional networks
Background Advances in microbiome science are being driven in large part due to our
ability to study and infer microbial ecology from genomes reconstructed from mixed …
ability to study and infer microbial ecology from genomes reconstructed from mixed …
CeMbio - The Caenorhabditis elegans Microbiome Resource
The study of microbiomes by sequencing has revealed a plethora of correlations between
microbial community composition and various life-history characteristics of the …
microbial community composition and various life-history characteristics of the …
Microbial regulation of hexokinase 2 links mitochondrial metabolism and cell death in colitis
F Hinrichsen, J Hamm, M Westermann, L Schröder… - Cell Metabolism, 2021 - cell.com
Hexokinases (HK) catalyze the first step of glycolysis limiting its pace. HK2 is highly
expressed in gut epithelium, contributes to immune responses, and is upregulated during …
expressed in gut epithelium, contributes to immune responses, and is upregulated during …
Genome-scale models in human metabologenomics
Metabologenomics integrates metabolomics with other omics data types to comprehensively
study the genetic and environmental factors that influence metabolism. These multi-omics …
study the genetic and environmental factors that influence metabolism. These multi-omics …
Teasing out missing reactions in genome-scale metabolic networks through hypergraph learning
Abstract GEnome-scale Metabolic models (GEMs) are powerful tools to predict cellular
metabolism and physiological states in living organisms. However, due to our imperfect …
metabolism and physiological states in living organisms. However, due to our imperfect …