Molecular Mechanism of Organic Crystal Nucleation: A Perspective of Solution Chemistry and Polymorphism
J Zhou, Y Zhou, W Tang - Crystals, 2022 - mdpi.com
Crystal nucleation determining the formation and assembly pathway of first organic materials
is the central science of various scientific disciplines such as chemical, geochemical …
is the central science of various scientific disciplines such as chemical, geochemical …
Three-step mechanism of antisolvent crystallization
Synthesis of crystalline materials involves the two most important methods: antisolvent and
cooling crystallization. Despite the extensive use of the antisolvent method in the …
cooling crystallization. Despite the extensive use of the antisolvent method in the …
Unveiling the conformational landscape of tizanidine and its effects on selective nucleation: Enabling controlled manipulation of polymorphs and solvates
D Wu, S Li, Y Feng, C Chen, L Fu, G Chen… - Separation and …, 2025 - Elsevier
The intricate relationship between conformational diversity and polymorphic nucleation is
evident, while the underlying mechanisms remain unclear. In this work, tizanidine (TZND) …
evident, while the underlying mechanisms remain unclear. In this work, tizanidine (TZND) …
Emulsification of Supersaturated Solutions Amplifies Induction Time Variation in Crystallization
The induction time for the onset of nucleation is known to decrease with increasing solution
supersaturation. A large variation in induction time is experimentally observed for various …
supersaturation. A large variation in induction time is experimentally observed for various …
Unraveling the complexity of amorphous solid as direct ingredient for conventional oral solid dosage form: The story of Elagolix Sodium
Conventional solid oral dosage form development is not typically challenged by reliance on
an amorphous drug substance as a direct ingredient in the drug product, as this may result …
an amorphous drug substance as a direct ingredient in the drug product, as this may result …
[HTML][HTML] Group contribution method for rapid estimation of crystal growth rates
The morphological evolution of organic crystals during crystallization depends on the face-
specific growth rates. Classical growth rate models relate the face-specific growth rates to …
specific growth rates. Classical growth rate models relate the face-specific growth rates to …
Multiscale Computational Model for Polymorphism and Growth of Crystals in Solution Crystallization
AV Dighe - 2022 - search.proquest.com
Understanding the self-assembly of molecules during crystallization is critical for the precise
synthesis of crystalline materials. Diverse types of materials such nanomaterials, active …
synthesis of crystalline materials. Diverse types of materials such nanomaterials, active …