COVID-19: challenges of viral variants

JL Jacobs, G Haidar, JW Mellors - Annual Review of Medicine, 2023 - annualreviews.org
The COVID-19 pandemic has been accompanied by SARS-CoV-2 evolution and
emergence of viral variants that have far exceeded initial expectations. Five major variants of …

Fitness, growth and transmissibility of SARS-CoV-2 genetic variants

E Volz - Nature Reviews Genetics, 2023 - nature.com
The massive scale of the global SARS-CoV-2 sequencing effort created new opportunities
and challenges for understanding SARS-CoV-2 evolution. Rapid detection and assessment …

Outbreak. info genomic reports: scalable and dynamic surveillance of SARS-CoV-2 variants and mutations

K Gangavarapu, AA Latif, JL Mullen, M Alkuzweny… - Nature …, 2023 - nature.com
In response to the emergence of SARS-CoV-2 variants of concern, the global scientific
community, through unprecedented effort, has sequenced and shared over 11 million …

Assessing transmissibility of SARS-CoV-2 lineage B. 1.1. 7 in England

E Volz, S Mishra, M Chand, JC Barrett, R Johnson… - Nature, 2021 - nature.com
Abstract The SARS-CoV-2 lineage B. 1.1. 7, designated variant of concern (VOC) 202012/01
by Public Health England, was first identified in the UK in late summer to early autumn 2020 …

Nextstrain: real-time tracking of pathogen evolution

J Hadfield, C Megill, SM Bell, J Huddleston… - …, 2018 - academic.oup.com
Understanding the spread and evolution of pathogens is important for effective public health
measures and surveillance. Nextstrain consists of a database of viral genomes, a …

Cryptic transmission of SARS-CoV-2 in Washington state

T Bedford, AL Greninger, P Roychoudhury, LM Starita… - Science, 2020 - science.org
After its emergence in Wuhan, China, in late November or early December 2019, the severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus rapidly spread globally …

TreeTime: Maximum-likelihood phylodynamic analysis

P Sagulenko, V Puller, RA Neher - Virus evolution, 2018 - academic.oup.com
Mutations that accumulate in the genome of cells or viruses can be used to infer their
evolutionary history. In the case of rapidly evolving organisms, genomes can reveal their …

Epidemiological and evolutionary considerations of SARS-CoV-2 vaccine dosing regimes

CM Saad-Roy, SE Morris, CJE Metcalf, MJ Mina… - Science, 2021 - science.org
INTRODUCTION As the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
pandemic continues, the deployment of safe and effective vaccines presents a key …

[HTML][HTML] Underdetected dispersal and extensive local transmission drove the 2022 mpox epidemic

MI Paredes, N Ahmed, M Figgins, V Colizza, P Lemey… - Cell, 2024 - cell.com
Summary The World Health Organization declared mpox a public health emergency of
international concern in July 2022. To investigate global mpox transmission and population …

Vaccine nationalism and the dynamics and control of SARS-CoV-2

CE Wagner, CM Saad-Roy, SE Morris, RE Baker… - Science, 2021 - science.org
INTRODUCTION The COVID-19 pandemic has imposed massive public health burdens and
economic costs, with more than 220 million confirmed cases and more than 4.5 million …