Mouse models of atherosclerosis and their suitability for the study of myocardial infarction
Atherosclerotic plaques impair vascular function and can lead to arterial obstruction and
tissue ischaemia. Rupture of an atherosclerotic plaque within a coronary artery can result in …
tissue ischaemia. Rupture of an atherosclerotic plaque within a coronary artery can result in …
[HTML][HTML] Natural and synthetic antioxidants targeting cardiac oxidative stress and redox signaling in cardiometabolic diseases
M Barteková, A Adameová, A Görbe… - Free Radical Biology …, 2021 - Elsevier
Cardiometabolic diseases (CMDs) are metabolic diseases (eg, obesity, diabetes,
atherosclerosis, rare genetic metabolic diseases, etc.) associated with cardiac pathologies …
atherosclerosis, rare genetic metabolic diseases, etc.) associated with cardiac pathologies …
Interaction of cardiovascular nonmodifiable risk factors, comorbidities and comedications with ischemia/reperfusion injury and cardioprotection by pharmacological …
Preconditioning, postconditioning, and remote conditioning of the myocardium enhance the
ability of the heart to withstand a prolonged ischemia/reperfusion insult and the potential to …
ability of the heart to withstand a prolonged ischemia/reperfusion insult and the potential to …
Influence of cardiometabolic comorbidities on myocardial function, infarction, and cardioprotection: Role of cardiac redox signaling
The morbidity and mortality from cardiovascular diseases (CVD) remain high. Metabolic
diseases such as obesity, hyperlipidemia, diabetes mellitus (DM), non-alcoholic fatty liver …
diseases such as obesity, hyperlipidemia, diabetes mellitus (DM), non-alcoholic fatty liver …
Octacosanol and health benefits: Biological functions and mechanisms of action
Y Zhou, F Cao, F Luo, Q Lin - Food Bioscience, 2022 - Elsevier
Octacosanol is a widely distributed natural higher aliphatic alcohol that can be isolated and
purified from rice bran, sugarcane, beeswax, insect wax, etc. Octacosanol exerts various …
purified from rice bran, sugarcane, beeswax, insect wax, etc. Octacosanol exerts various …
Preclinical models of myocardial infarction: from mechanism to translation
TP Martin, EA MacDonald… - British Journal of …, 2022 - Wiley Online Library
Approximately 7 million people are affected by acute myocardial infarction (MI) each year,
and despite significant therapeutic and diagnostic advancements, MI remains a leading …
and despite significant therapeutic and diagnostic advancements, MI remains a leading …
PCSK9 in myocardial infarction and cardioprotection: importance of lipid metabolism and inflammation
Extensive evidence from epidemiologic, genetic, and clinical intervention studies has
indisputably shown that elevated low-density lipoprotein cholesterol (LDL-C) concentrations …
indisputably shown that elevated low-density lipoprotein cholesterol (LDL-C) concentrations …
The influence of metabolic risk factors on the inflammatory response triggered by myocardial infarction: bridging pathophysiology to treatment
L Ramos-Regalado, S Alcover, L Badimon, G Vilahur - Cells, 2024 - mdpi.com
Myocardial infarction (MI) sets off a complex inflammatory cascade that is crucial for effective
cardiac healing and scar formation. Yet, if this response becomes excessive or uncontrolled …
cardiac healing and scar formation. Yet, if this response becomes excessive or uncontrolled …
Recombinant human soluble domain of CD39L3 and ticagrelor: cardioprotective effects in experimental myocardial infarction
G Vilahur, M Radike, P Sutelman… - European Heart …, 2024 - academic.oup.com
Abstract Background and Aims The ecto–nucleoside triphosphate diphosphohydrolases of
the CD39 family degrade ATP and ADP into AMP, which is converted into adenosine by the …
the CD39 family degrade ATP and ADP into AMP, which is converted into adenosine by the …
[HTML][HTML] Hepatoprotective and cardioprotective effects of empagliflozin in spontaneously hypertensive rats fed a high-fat diet
S Hojná, H Malínská, M Hüttl, Z Vaňourková… - Biomedicine & …, 2024 - Elsevier
A combination of liver and heart dysfunction worsens the prognosis of human survival. The
aim of this study was to investigate whether empagliflozin (a sodium-glucose transporter-2 …
aim of this study was to investigate whether empagliflozin (a sodium-glucose transporter-2 …