Since cancer stem cells (CSCs) were first identified in leukemia in 1994, they have been
considered promising therapeutic targets for cancer therapy. These cells have self-renewal …

Abstract Tumorigenic Cancer Stem Cells (CSCs), often called tumor-initiating cells (TICs),
represent a unique subset of cells within the tumor milieu. They stand apart from the bulk of …

Bladder cancer is one of the concerning malignancies worldwide, which is lacking effective
targeted therapy. Gene therapy is a potential approach for bladder cancer treatment. While …

Bladder cancer is one of the most prevalent genitourinary cancers responsible for about
150,000 deaths per year worldwide. Currently, several treatments, such as endoscopic and …

Cancer is characterized by an abnormal growth of the cells in an uncontrolled manner.
These cells have the potential to invade and can eventually turn into malignancy, leading to …

Among cell surface markers, CD44 is considered the main marker for identifying and
isolating the cancer stem cells (CSCs) among other cells and has attracted significant …

Triple-negative breast cancer (TNBC) is distinguished by negative expression of estrogen
receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 …

Objective Gastric cancer is a multifactorial disease. In addition to environmental factors,
many genes are involved in this malignancy. One of the genes associated with gastric …

The cell surface adhesion receptor CD44 reportedly affects the development and
progression of cancers. Moreover, CD44 gene rs187115 polymorphism appears to be …

Background We conducted a meta-analysis to evaluate the relationship between the
glutathione S-transferase μ1 (GSTM1)–and glutathione S-transferase θ1 (GSTT1)–null …