Quantifying the microstructural and macrostructural geometrical features of the human
brain's connections is necessary for understanding normal aging and disease. Here, we …

The value of normative models in research and clinical practice relies on their robustness
and a systematic comparison of different modelling algorithms and parameters; however …

Sex and gender—biological and social constructs—significantly impact the prevalence of
protective and risk factors, influencing the burden of Alzheimer's disease (AD; amyloid beta …

While major psychiatric disorders lack signature diagnostic neuropathologies akin to
dementias, classic postmortem studies have established microstructural involvement, ie …

Cerebral small vessel disease (cSVD) is a leading cause of stroke and dementia. Genetic
risk loci for white matter hyperintensities (WMH), the most common MRI-marker of cSVD in …

Purpose Neurite orientation dispersion and density imaging (NODDI) provides measures of
neurite density and dispersion through computation of the neurite density index (NDI) and …

Biological sex is a crucial variable in neuroscience studies where sex differences have been
documented across cognitive functions and neuropsychiatric disorders. While gross …

Unveiling the details of white matter (WM) maturation throughout ageing is a fundamental
question for understanding the ageing brain. In an extensive comparison of brain age …

The relationship between brain microstructure and aging has been the subject of intense
study, with diffusion MRI perhaps the most effective modality for elucidating these …

Brain age refers to age predicted by brain features. Brain age has previously been
associated with various health and disease outcomes and suggested as a potential …