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DNA synthesis technologies to close the gene writing gap
Synthetic DNA is of increasing demand across many sectors of research and commercial
activities. Engineering biology, therapy, data storage and nanotechnology are set for rapid …
activities. Engineering biology, therapy, data storage and nanotechnology are set for rapid …
Hydrogels as functional components in artificial cell systems
Recent years have seen substantial efforts aimed at constructing artificial cells from various
molecular components with the aim of mimicking the processes, behaviours and …
molecular components with the aim of mimicking the processes, behaviours and …
Molecular dynamics simulation of an entire cell
The ultimate microscope, directed at a cell, would reveal the dynamics of all the cell's
components with atomic resolution. In contrast to their real-world counterparts …
components with atomic resolution. In contrast to their real-world counterparts …
Cell-free gene expression
D Garenne, MC Haines, EF Romantseva… - Nature reviews …, 2021 - nature.com
Cell-free gene expression (CFE) emerged as an alternative approach to living cells for
specific applications in protein synthesis and labelling for structural biology and proteomics …
specific applications in protein synthesis and labelling for structural biology and proteomics …
Rapid reconstruction of SARS-CoV-2 using a synthetic genomics platform
T Thi Nhu Thao, F Labroussaa, N Ebert, P V'kovski… - Nature, 2020 - nature.com
Reverse genetics has been an indispensable tool to gain insights into viral pathogenesis
and vaccine development. The genomes of large RNA viruses, such as those from …
and vaccine development. The genomes of large RNA viruses, such as those from …
Total synthesis of Escherichia coli with a recoded genome
Nature uses 64 codons to encode the synthesis of proteins from the genome, and chooses 1
sense codon—out of up to 6 synonyms—to encode each amino acid. Synonymous codon …
sense codon—out of up to 6 synonyms—to encode each amino acid. Synonymous codon …
Emerging technologies in algal biotechnology: toward the establishment of a sustainable, algae-based bioeconomy
Mankind has recognized the value of land plants as renewable sources of food, medicine,
and materials for millennia. Throughout human history, agricultural methods were …
and materials for millennia. Throughout human history, agricultural methods were …
The emergence of adaptive laboratory evolution as an efficient tool for biological discovery and industrial biotechnology
Harnessing the process of natural selection to obtain and understand new microbial
phenotypes has become increasingly possible due to advances in culturing techniques …
phenotypes has become increasingly possible due to advances in culturing techniques …
Chemically and biologically engineered bacteria‐based delivery systems for emerging diagnosis and advanced therapy
Bacteria are one of the main groups of organisms, which dynamically and closely participate
in human health and disease development. With the integration of chemical biotechnology …
in human health and disease development. With the integration of chemical biotechnology …
Tumour-targeting bacteria engineered to fight cancer
S Zhou, C Gravekamp, D Bermudes, K Liu - Nature Reviews Cancer, 2018 - nature.com
Recent advances in targeted therapy and immunotherapy have once again raised the hope
that a cure might be within reach for many cancer types. Yet, most late-stage cancers are …
that a cure might be within reach for many cancer types. Yet, most late-stage cancers are …