[HTML][HTML] The immune microenvironment in cartilage injury and repair

M Li, H Yin, Z Yan, H Li, J Wu, Y Wang, F Wei, G Tian… - Acta Biomaterialia, 2022 - Elsevier
The ability of articular cartilage to repair itself is limited because it lacks blood vessels,
nerves, and lymph tissue. Once damaged, it can lead to joint swelling and pain, accelerating …

Knee articular cartilage repair and restoration techniques: a review of the literature

DL Richter, RC Schenck Jr, DC Wascher… - Sports …, 2016 - journals.sagepub.com
Context: Isolated chondral and osteochondral defects of the knee are a difficult clinical
challenge, particularly in younger patients for whom alternatives such as partial or total knee …

[HTML][HTML] An educational review of cartilage repair: precepts & practice–myths & misconceptions–progress & prospects

EB Hunziker, K Lippuner, MJB Keel… - Osteoarthritis and …, 2015 - Elsevier
Objective The repair of cartilaginous lesions within synovial joints is still an unresolved and
weighty clinical problem. Although research activity in this area has been indefatigably …

[HTML][HTML] Surgical therapy in osteoarthritis

H Madry - Osteoarthritis and cartilage, 2022 - Elsevier
Objective To provide an evidence-based overview of the different surgical procedures in
osteoarthritis (OA). Design This narrative review reports on surgical therapies (1) for severe …

Sulfated polysaccharide-based scaffolds for orthopaedic tissue engineering

J Dinoro, M Maher, S Talebian, M Jafarkhani… - Biomaterials, 2019 - Elsevier
Given their native-like biological properties, high growth factor retention capacity and porous
nature, sulfated-polysaccharide-based scaffolds hold great promise for a number of tissue …

Osteochondral allograft transplantation of the knee: analysis of failures at 5 years

RM Frank, S Lee, D Levy, S Poland… - … American journal of …, 2017 - journals.sagepub.com
Background: Osteochondral allograft transplantation (OAT) is being performed with
increasing frequency, and the need for reoperations is not uncommon. Purpose: To quantify …

[HTML][HTML] Cell-based articular cartilage repair: the link between development and regeneration

KL Caldwell, J Wang - Osteoarthritis and cartilage, 2015 - Elsevier
Clinical efforts to repair damaged articular cartilage (AC) currently face major obstacles due
to limited intrinsic repair capacity of the tissue and unsuccessful biological interventions …

Osteochondral allograft transplantation in cartilage repair: Graft storage paradigm, translational models, and clinical applications

WD Bugbee, AL Pallante‐Kichura… - Journal of …, 2016 - Wiley Online Library
The treatment of articular cartilage injury and disease has become an increasingly relevant
part of orthopaedic care. Articular cartilage transplantation, in the form of osteochondral …

Distal femoral varus osteotomy for the management of valgus deformity of the knee

SL Sherman, SF Thompson… - JAAOS-Journal of the …, 2018 - journals.lww.com
Distal femoral varus osteotomy is a well-described treatment option for patients with valgus
malalignment associated with a variety of underlying conditions. This procedure may be the …

Prospective assessment of outcomes after primary unipolar, multisurface, and bipolar osteochondral allograft transplantations in the knee: a comparison of 2 …

JP Stannard, JL Cook - The American Journal of Sports …, 2020 - journals.sagepub.com
Background: Articular cartilage lesions in the knee remain a challenging clinical problem.
Hypothesis: A novel graft preservation method combined with surgical technique and patient …