Pulmonary hypertension is defined as a resting mean pulmonary artery pressure of 25 mm
Hg or above. This review deals with pulmonary arterial hypertension (PAH), a type of …

Perivascular inflammation is a prominent pathologic feature in most animal models of
pulmonary hypertension (PH) as well as in pulmonary arterial hypertension (PAH) patients …

Lymphedema is a common, complex, and inexplicably underappreciated human disease.
Despite a history of relative neglect by health care providers and by governmental health …

Leukotrienes are powerful immune-regulating lipid mediators with established pathogenic
roles in inflammatory allergic diseases of the respiratory tract—in particular, asthma and hay …

This review seeks to provide an update of preclinical findings and available clinical data on
the chronic persistent inflammation and its direct role on the pulmonary arterial hypertension …

Rationale: Pulmonary arterial hypertension (PH) is a life-threatening condition associated
with immune dysregulation and abnormal regulatory T cell (Treg) activity, but it is currently …

The lymphatic system is essential for the maintenance of tissue fluid homeostasis,
gastrointestinal lipid absorption, and immune trafficking. Whereas lymphatic regeneration …

Leukotrienes are biologically active eicosanoid lipid mediators that originate from oxidative
metabolism of arachidonic acid. Biosynthesis of leukotrienes involves a set of soluble and …

Abstract Purpose of Review This review focuses on the therapeutic management and
individualized approach to Group 1 pulmonary arterial hypertension (PAH), utilizing Food …

Background: Bmpr2 (bone morphogenetic protein receptor 2) mutations are critical risk
factors for hereditary pulmonary arterial hypertension (PAH) with approximately 20% of …