Biological functions of RNA molecules are dependent upon sustained specific three-
dimensional (3D) structures of RNA, with or without the help of proteins. Understanding of …

RNA-Puzzles is a collective endeavor dedicated to the advancement and improvement of
RNA three-dimensional structure prediction. With agreement from structural biologists, RNA …

Significant improvements have been made in the efficiency and accuracy of RNA 3D
structure prediction methods during the succeeding challenges of RNA-Puzzles, a …

RNA is a unique biomolecule that is involved in a variety of fundamental biological functions,
all of which depend solely on its structure and dynamics. Since the experimental …

In RNA structural biology and bioinformatics an access to correct RNA secondary structure
and its proper representation is of crucial importance. This is true especially in the field of …

Understanding the numerous functions of RNAs depends critically on the knowledge of their
three-dimensional (3D) structure. In contrast to the protein field, a much smaller number of …

There is an increasing need for determining 3D structures of DNAs, eg, for increasing the
efficiency of DNA aptamer selection. Recently, we have proposed a computational method …

Motivation Tertiary structure alignment is one of the main challenges in the computer-aided
comparative study of molecular structures. Its aim is to optimally overlay the 3D shapes of …

In silico prediction is a well-established approach to derive a general shape of an RNA
molecule based on its sequence or secondary structure. This paper reports an analysis of …

In the 1970s, computer scientists began to engage in research in the field of structural
biology. The first structural databases, as well as models and methods supporting the …