Innovative tools for mechanobiology: unraveling outside-in and inside-out mechanotransduction
Cells and tissues can sense and react to the modifications of the physico-chemical
properties of the extracellular environment (ECM) through integrin-based adhesion sites and …
properties of the extracellular environment (ECM) through integrin-based adhesion sites and …
Looking into the future: toward advanced 3D biomaterials for stem‐Cell‐based regenerative medicine
Z Liu, M Tang, J Zhao, R Chai, J Kang - Advanced Materials, 2018 - Wiley Online Library
Stem‐cell‐based therapies have the potential to provide novel solutions for the treatment of
a variety of diseases, but the main obstacles to such therapies lie in the uncontrolled …
a variety of diseases, but the main obstacles to such therapies lie in the uncontrolled …
Bioinspired membrane provides periosteum-mimetic microenvironment for accelerating vascularized bone regeneration
Periosteum plays a pivotal role in vascularization, ossification and remodeling during the
healing process of bone injury. However, there are few studies focused on the construction …
healing process of bone injury. However, there are few studies focused on the construction …
[HTML][HTML] Cellular modulation by the mechanical cues from biomaterials for tissue engineering
Q Wei, S Wang, F Han, H Wang, W Zhang… - Biomaterials …, 2021 - ncbi.nlm.nih.gov
Mechanical cues from the extracellular matrix (ECM) microenvironment are known to be
significant in modulating the fate of stem cells to guide developmental processes and …
significant in modulating the fate of stem cells to guide developmental processes and …
A 2020 view of tension-based cortical morphogenesis
DC Van Essen - Proceedings of the National Academy of …, 2020 - National Acad Sciences
Mechanical tension along the length of axons, dendrites, and glial processes has been
proposed as a major contributor to morphogenesis throughout the nervous system [DC Van …
proposed as a major contributor to morphogenesis throughout the nervous system [DC Van …
Pushing the natural frontier: Progress on the integration of biomaterial cues toward combinatorial biofabrication and tissue engineering
The engineering of fully functional, biological‐like tissues requires biomaterials to direct
cellular events to a near‐native, 3D niche extent. Natural biomaterials are generally seen as …
cellular events to a near‐native, 3D niche extent. Natural biomaterials are generally seen as …
The influence of the stiffness of GelMA substrate on the outgrowth of PC12 cells
Y Wu, Y **ang, J Fang, X Li, Z Lin, G Dai, J Yin… - Bioscience …, 2019 - portlandpress.com
Recent studies have shown the importance of cell–substrate interaction on neurone
outgrowth, where the Young's modulus of the matrix plays a crucial role on the neurite …
outgrowth, where the Young's modulus of the matrix plays a crucial role on the neurite …
Multiscale mechanobiology in brain physiology and diseases
Increasing evidence suggests that mechanics play a critical role in regulating brain function
at different scales. Downstream integration of mechanical inputs into biochemical signals …
at different scales. Downstream integration of mechanical inputs into biochemical signals …
Layer-by-layer ultraviolet assisted extrusion-based (UAE) bioprinting of hydrogel constructs with high aspect ratio for soft tissue engineering applications
One of the major challenges in the field of soft tissue engineering using bioprinting is
fabricating complex tissue constructs with desired structure integrity and mechanical …
fabricating complex tissue constructs with desired structure integrity and mechanical …
Neural stem cell delivery using brain-derived tissue-specific bioink for recovering from traumatic brain injury
Traumatic brain injury is one of the leading causes of accidental death and disability. The
loss of parts in a severely injured brain induces edema, neuronal apoptosis, and …
loss of parts in a severely injured brain induces edema, neuronal apoptosis, and …