The role of macrophage migration inhibitory factor (MIF) in autoimmunity is underscored by
data showing that common functional polymorphisms in MIF are associated with disease …

Macrophage migration inhibitory factor (MIF) accounts for one of the first cytokine activities to
have been described, and it has emerged recently to be an important regulator of innate and …

Juvenile idiopathic arthritis (JIA) refers to a group of chronic childhood arthropathies of
unknown etiology, currently classified into subtypes primarily on the basis of clinical …

Produced by many cell types, macrophage migration inhibitory factor (MIF) is a pleiotropic
cytokine with critical and supporting roles in many disease states and conditions. Its disease …

Juvenile idiopathic arthritis (JIA) is the most common chronic arthropathy of childhood which
is believed to be influenced by both genetic and environmental factors. The progress in …

Sepsis is a polygenic and complex syndrome that is initiated by infection and is
characterized by a systemic inflammatory response. Genetic polymorphisms in the immune …

Objective To address the functional and prognostic relevance of the− 173 single‐nucleotide
G‐to‐C polymorphism of the macrophage migration inhibitory factor (MIF) gene in patients …

Many of the genes that affect aging and longevity in model organisms, such as mice, fruit
flies, and worms, have human homologs. This article reviews several genetic pathways that …

Objective Patients with systemic juvenile idiopathic arthritis (JIA) have arthritis, quotidian
fevers, and other extraarticular features. This disease often remains severe and debilitating …

Macrophage migration inhibitory factor (MIF) is a pleiotropic cytokine produced by the
pituitary gland and multiple cell types, including macrophages (Mø), dendritic cells (DC) and …