Isothermal amplification of nucleic acids is a simple process that rapidly and efficiently
accumulates nucleic acid sequences at constant temperature. Since the early 1990s …

Droplet-based microfluidic systems have been employed to manipulate discrete fluid
volumes with immiscible phases. Creating the fluid droplets at microscale has led to a …

Rolling circle amplification (RCA) is an isothermal enzymatic process where a short DNA or
RNA primer is amplified to form a long single stranded DNA or RNA using a circular DNA …

Blood stream infection or sepsis is a major health problem worldwide, with extremely high
mortality, which is partly due to the inability to rapidly detect and identify bacteria in the early …

Diagnostic tools for biomolecular detection need to fulfill specific requirements in terms of
sensitivity, selectivity and high-throughput in order to widen their applicability and to …

Rapid and timely diagnosis of infectious diseases is a critical determinant of clinical
outcomes and general public health. For the detection of various pathogens, microfluidics …

Pathogen detection is growing in importance in the global health arena because of the high
morbidity and mortality associated with bacterial blood stream infections. In this work, we …

Nucleic acid amplification technology (NAAT) has assumed a critical position in disease
diagnosis in recent times and contributed significantly to healthcare. Application of these …

Vector-borne diseases are a major concern for human health globally, especially malaria in
densely populated, less developed, tropical regions of the world. Malaria causes loss of …

A polymerase chain reaction (PCR) is a method typically active in genetic research,
especially to amplify or copy genes. Herein, the application of microfluidic devices for …