The year 2004 represents a milestone for the biosensor research community: in this year,
over 1000 articles were published describing experiments performed using commercially …

抄録 細胞膜は細胞と外部環境との間のコミュニケーションのためのインターフェイスとしてゆるぎ
ない役割をもつ. したがって外部シグナルに対する細胞の反応性や応答能力は, 細胞表面の決定基 …

Human galectin-1 is a potent multifunctional effector that participates in specific protein–
carbohydrate and protein–protein (lipid) interactions. By determining its X-ray structure, we …

Inhibitors for galectin-1 and-3 were synthesized from thiodigalactoside and lactosamine by
derivatization of the galactose C3. Introduction of 4-phenyl-1 H-1, 2, 3-triazol-1-yl …

More and more studies report on the roles that galectins play in numerous types of cancer.
These roles can be varied, as has been shown particularly for galectin‐3. These studies …

Objective: To determine the expression of endogenous adhesion/growth-regulatory lectins
and their binding sites using labeled tissue lectins as well as the binding profile of …

The growth‐regulatory interplay between ganglioside GM1 on human SK‐N‐MC
neuroblastoma cells and an endogenous lectin provides a telling example for glycan …

Publisher Summary This chapter focuses on hevein domains and presents an attractive
model to study carbohydrate–protein interactions at atomic resolution. Among the various …

Galectins are a family of galactose binding lectins that have become the focus of attention of
cancer biologists due to their numerous regulatory roles in normal cellular metabolism and …

Sugar-encoded information of glycoconjugates is translated into cellular responses by
endogenous lectins. Galectins stand out against other lectin families due to their wide range …