Towards the elimination of chronic obstructive pulmonary disease: a Lancet Commission

D Stolz, T Mkorombindo, DM Schumann, A Agusti… - The Lancet, 2022‏ - thelancet.com
Executive summary Despite substantial progress in reducing the global impact of many non-
communicable diseases, including heart disease and cancer, morbidity and mortality due to …

[HTML][HTML] Clinical significance and applications of oscillometry

DA Kaminsky, SJ Simpson, KI Berger… - European …, 2022‏ - publications.ersnet.org
Recently,“Technical standards for respiratory oscillometry” was published, which reviewed
the physiological basis of oscillometric measures and detailed the technical factors related …

[HTML][HTML] Physical, cognitive, and mental health impacts of COVID-19 after hospitalisation (PHOSP-COVID): a UK multicentre, prospective cohort study

RA Evans, HJC McAuley, EM Harrison… - The Lancet …, 2021‏ - thelancet.com
Background The impact of COVID-19 on physical and mental health and employment after
hospitalisation with acute disease is not well understood. The aim of this study was to …

Effects of dupilumab on mucus plugging and ventilation defects in patients with moderate-to-severe asthma: a randomized, double-blind, placebo-controlled trial

S Svenningsen, M Kjarsgaard, E Haider… - American Journal of …, 2023‏ - atsjournals.org
Methods We completed a single-center, randomized, double-blind, placebo-controlled trial
(ClinicalTrials. gov identifier NCT 03884842) in 25 adults with uncontrolled moderate to …

Telemedicine in COPD: an overview by topics

MT Barbosa, CS Sousa, M Morais-Almeida… - COPD: Journal of …, 2020‏ - Taylor & Francis
COPD is a major cause of morbidity and mortality worldwide and carries a huge and
growing economic and social burden. Telemedicine might allow the care of patients with …

Pulmonary function testing in COPD: looking beyond the curtain of FEV1

S Kakavas, OS Kotsiou, F Perlikos, M Mermiri… - NPJ primary care …, 2021‏ - nature.com
Chronic obstructive pulmonary disease (COPD) management remains challenging due to
the high heterogeneity of clinical symptoms and the complex pathophysiological basis of the …

Preserved ratio impaired spirometry is associated with small airway dysfunction and reduced total lung capacity

N Zhao, F Wu, J Peng, Y Zheng, H Tian, H Yang… - Respiratory …, 2022‏ - Springer
Background: Preserved ratio impaired spirometry (PRISm) refers to decreased forced
expiratory volume in 1 s (FEV1) in the setting of preserved ratio. Little is known about the …

Airway smooth muscle function in asthma

D **ong, JG Martin, AM Lauzon - Frontiers in physiology, 2022‏ - frontiersin.org
Known to have affected around 340 million people across the world in 2018, asthma is a
prevalent chronic inflammatory disease of the airways. The symptoms such as wheezing …

Addressing reduced laboratory-based pulmonary function testing during a pandemic

A Kouri, S Gupta, A Yadollahi, CM Ryan, AS Gershon… - Chest, 2020‏ - Elsevier
To reduce the spread of the severe acute respiratory syndrome coronavirus 2, many
pulmonary function testing (PFT) laboratories have been closed or have significantly …

[HTML][HTML] Asthma control, airway mucus, and 129Xe MRI ventilation after a single benralizumab dose

MJ McIntosh, HK Kooner, RL Eddy, S Jeimy, C Licskai… - Chest, 2022‏ - Elsevier
Background Patients with eosinophilic asthma often report poor symptomatic control and
quality of life. Anti-IL-5 therapy, including anti-IL-5Rα (benralizumab), rapidly depletes …