Quantitative phase imaging: recent advances and expanding potential in biomedicine

TL Nguyen, S Pradeep, RL Judson-Torres, J Reed… - ACS …, 2022 - ACS Publications
Quantitative phase imaging (QPI) is a label-free, wide-field microscopy approach with
significant opportunities for biomedical applications. QPI uses the natural phase shift of light …

Review of quantitative phase-digital holographic microscopy: promising novel imaging technique to resolve neuronal network activity and identify cellular biomarkers …

P Marquet, C Depeursinge, PJ Magistretti - Neurophotonics, 2014 - spiedigitallibrary.org
Quantitative phase microscopy (QPM) has recently emerged as a new powerful quantitative
imaging technique well suited to noninvasively explore a transparent specimen with a …

Stain-free identification of cell nuclei using tomographic phase microscopy in flow cytometry

D Pirone, J Lim, F Merola, L Miccio, M Mugnano… - Nature …, 2022 - nature.com
Quantitative phase imaging has gained popularity in bioimaging because it can avoid the
need for cell staining, which, in some cases, is difficult or impossible. However, as a result …

Ptychography–a label free, high-contrast imaging technique for live cells using quantitative phase information

J Marrison, L Räty, P Marriott, P O'Toole - Scientific reports, 2013 - nature.com
Cell imaging often relies on synthetic or genetic fluorescent labels, to provide contrast which
can be far from ideal for imaging cells in their in vivo state. We report on the biological …

Generalized cell morphological parameters based on interferometric phase microscopy and their application to cell life cycle characterization

P Girshovitz, NT Shaked - Biomedical optics express, 2012 - opg.optica.org
We present analysis tools which are formulated using wide-field interferometric phase
microscopy measurements, and show their ability to uniquely quantify the life cycle of live …

Compact and portable low-coherence interferometer with off-axis geometry for quantitative phase microscopy and nanoscopy

P Girshovitz, NT Shaked - Optics express, 2013 - opg.optica.org
We present a simple-to-align, highly-portable interferometer, which is able to capture wide-
field, off-axis interference patterns from transparent samples under low-coherence …

Tomographic phase microscopy of living three-dimensional cell cultures

A Kuś, M Dudek, B Kemper… - … of biomedical optics, 2014 - spiedigitallibrary.org
A successful application of self-interference digital holographic microscopy in combination
with a sample-rotation-based tomography module for three-dimensional (3-D) label-free …

Dehydration of plant cells shoves nuclei rotation allowing for 3D phase-contrast tomography

Z Wang, V Bianco, D Pirone, P Memmolo… - Light: Science & …, 2021 - nature.com
Single-cell phase-contrast tomography promises to become decisive for studying 3D
intracellular structures in biology. It involves probing cells with light at wide angles, which …

Doubling the field of view in off-axis low-coherence interferometric imaging

P Girshovitz, NT Shaked - Light: Science & Applications, 2014 - nature.com
We present a new interferometric and holographic approach, named interferometry with
doubled imaging area (IDIA), with which it is possible to double the camera field of view …

Quantitative phase imaging for cell culture quality control

L Kastl, M Isbach, D Dirksen… - Cytometry Part …, 2017 - Wiley Online Library
The potential of quantitative phase imaging (QPI) with digital holographic microscopy (DHM)
for quantification of cell culture quality was explored. Label‐free QPI of detached single cells …