Abstract The 'Vascular Depression'hypothesis posits that cerebrovascular disease may
predispose, precipitate or perpetuate some geriatric depressive syndromes. This hypothesis …

Depression remains a debilitating condition with an uncertain aetiology. Recently, attention
has been given to the renin–angiotensin system. In the central nervous system, angiotensin …

COVID-19 and the renin-angiotensin system (RAS) are linked by angiotensin-converting
enzyme 2 (ACE2), a key enzyme in RAS that has been validated as a SARS-CoV-2 receptor …

Emotional disorders, including depression and anxiety, contribute considerably to morbidity
across the world. Depression is a serious condition and is projected to be the top contributor …

Depression is a mood disorder characterized by abnormal thoughts. The pathophysiology of
depression is related to the deficiency of serotonin (5HT), which is derived from tryptophan …

A bidirectional relationship exists between hypertension and psychiatric disorders, including
unipolar and bipolar depression, anxiety, post-traumatic stress disorder (PTSD), psychosis …

Background and Objectives: The aim of this systematic review was to analyse which
candidate genes were examined in genetic association studies and their association with …

Major psychiatric disorders such as schizophrenia, major depressive and bipolar disorders
are severe, chronic and debilitating, and are associated with high disease burden and …

Background. Although it is common knowledge that the coronavirus disease of 2019 (COVID-
19) and other viral infections have an uneven impact globally, the reasons for this are still …

Background The comorbidity of major depressive disorder (MDD) and stroke are common in
clinic. There is a growing body of evidence suggesting a bi-directional relationship between …