Neurological and Neurobehavioral Disorders Associated with Toxoplasma gondii Infection in Humans

MA Virus, EG Ehrhorn, LAM Lui… - Journal of parasitology …, 2021 - Wiley Online Library
The intracellular parasite Toxoplasma gondii is estimated to infect up to 30% of the world
population, leading to lifelong chronic infection of the brain and muscle tissue. Although …

An updated meta-analysis of the association between Toxoplasma gondii infection and risk of epilepsy

M Sadeghi, SM Riahi, M Mohammadi… - Transactions of The …, 2019 - academic.oup.com
Toxoplasma gondii is a neurotropic pathogen with worldwide distribution. To evaluate the
association between Toxoplasma infection and the risk of epilepsy by meta-analysis …

Latent toxoplasmosis impairs learning and memory yet strengthens short-term and long-term hippocampal synaptic plasticity at perforant pathway-dentate gyrus, and …

S Choopani, B Kiani, S Aliakbari, J Babaie, M Golkar… - Scientific Reports, 2023 - nature.com
Investigating long-term potentiation (LTP) in disease models provides essential mechanistic
insight into synaptic dysfunction and relevant behavioral changes in many neuropsychiatric …

Catastrophic consequences: can the feline parasite Toxoplasma gondii prompt the purrfect neuroinflammatory storm following traumatic brain injury?

TL Baker, M Sun, BD Semple, S Tyebji… - Journal of …, 2020 - Springer
Traumatic brain injury (TBI) is one of the leading causes of morbidity and mortality
worldwide; however, treatment development is hindered by the heterogenous nature of TBI …

Toxoplasma gondii and Neospora caninum infection in epileptic dogs

G Morganti, G Rigamonti, MC Marchesi… - Journal of Small …, 2024 - Wiley Online Library
Objectives Studies in humans have demonstrated the role of Toxoplasma gondii, a
protozoan parasite, in epileptic seizures. This study aimed to investigate the serological …

Toxoplasma infection and risk of epilepsy: A case-control study of incident patients

AA Khatir, SA Moghaddam, M Almukhtar… - Microbial …, 2021 - Elsevier
Highlights•We assessed the relationship between T. gondii infection and epilepsy using
incident cases.•T. gondii infection was significantly associated with epilepsy (OR, 2.58; 95 …

α-Lipoic acid alleviates pentetrazol-induced neurological deficits and behavioral dysfunction in rats with seizures via an Nrf2 pathway

Y Cheng, F Luo, Q Zhang, Y Sang, X Chen, L Zhang… - RSC Advances, 2018 - pubs.rsc.org
Epilepsy (EP) is a type of chronic brain disease characterized by transient central nervous
system malfunction which is the result of neuron paradoxical discharge in the brain. In a …

Cannabinoid receptors and the proconvulsant effect of toxoplasmosis in mice

MM Ghanbari, M Joneidi, B Kiani, J Babaie… - Microbial …, 2020 - Elsevier
Toxoplasmosis is an infectious disease caused by the intracellular parasite Toxoplasma
gondii that harms the brain and increases the risk of epilepsy acquisition. It is well known …

A Double‐Edged Sword: Complement Component 3 in Toxoplasma gondii Infection

WY Huang, YP Wang, YS Mahmmod, JJ Wang… - …, 2019 - Wiley Online Library
Abstract Sprague Dawley rats and Kunming (KM) mice are artificially infected with type II
Toxoplasma gondii strain Prugniaud (Pru) to generate toxoplasmosis, which is a fatal …

[PDF][PDF] Toxoplasmosis among Egyptian children with neurological disorders: developmental and risk factors analysis

S El-Beshbishi, S Elzeky, R Atia… - Parasitologists …, 2020 - puj.journals.ekb.eg
Background: Toxoplasma gondii is a widespread neurotropic protozoan that influences the
CNS physiologywith a potential role in mediating congenital and neurodevelopmental …