The precise functional role of the hippocampus remains a topic of much debate. The
dominant view is that the dorsal (or posterior) hippocampus is implicated in memory and …

One literature treats the hippocampus as a purely cognitive structure involved in memory;
another treats it as a regulator of emotion whose dysfunction leads to psychopathology. We …

Recent large-scale collaborations are generating major surveys of cell types and
connections in the mouse brain, collecting large amounts of data across modalities, spatial …

The isocortex and hippocampal formation (HPF) in the mammalian brain play critical roles in
perception, cognition, emotion, and learning. We profiled∼ 1.3 million cells covering the …

Nervous systems are composed of various cell types, but the extent of cell type diversity is
poorly understood. We constructed a cellular taxonomy of one cortical region, primary visual …

The Cre/lox system is widely used in mice to achieve cell-type-specific gene expression.
However, a strong and universally responding system to express genes under Cre control is …

Adult hippocampal neurogenesis has been implicated in cognitive processes, such as
pattern separation, and in the behavioural effects of stress and antidepressants. Young adult …

Identifying the spatial organization of tissues at cellular resolution from single-cell gene
expression profiles is essential to understanding biological systems. Using an in situ 3D …

The hippocampal formation has been implicated in a growing number of disorders, from
Alzheimer's disease and cognitive ageing to schizophrenia and depression. How can the …

The hippocampus has a pivotal role in learning and in the formation and consolidation of
memory and is critically involved in the regulation of emotion, fear, anxiety, and stress …