Podocytopathies are kidney diseases in which direct or indirect podocyte injury drives
proteinuria or nephrotic syndrome. In children and young adults, genetic variants in> 50 …

The emergence of digital pathology—an image-based environment for the acquisition,
management and interpretation of pathology information supported by computational …

The ability to localize hundreds of macromolecules to discrete locations, structures and cell
types in a tissue is a powerful approach to understand the cellular and spatial organization …

The development of omics technologies has driven a profound expansion in the scale of
biological data and the increased complexity in internal dimensions, prompting the …

BACKGROUND It is unknown whether the risk of kidney disease progression and failure
differs between patients with and without genetic kidney disorders. METHODS Three cohorts …

Results Across 16 focus groups, 134 participants (range, 19–85 years old; 51% women),
including 101 patients and 33 caregivers, identified 58 outcomes. The ten highest-ranked …

Traditionally, pathological analysis and diagnosis are performed by manually eyeballing
glass-slide specimens under a microscope by an expert. The whole slide image (WSI) is the …

Over the past 2 decades, scoring systems for multiple glomerular diseases have emerged,
as have consortia of pathologists and nephrologists for the study of glomerular diseases …

Focal segmental glomerulosclerosis (FSGS) is a histologic pattern of injury defined by the
presence of sclerosis in some (segmental) of certain glomeruli (focal). On electron …

Diabetic kidney disease (DKD) is the leading cause of kidney failure and is associated with
substantial risk of cardiovascular disease, morbidity, and mortality. Traditionally, DKD …