Conspectus N-Acetylgalactosamine (GalNAc)-type O-glycosylation is an essential
posttranslational modification (PTM) that plays fundamental roles in biology. Malfunction of …

Lectins are widely distributed proteins having ability of binding selectively and reversibly
with carbohydrates moieties and glycoconjugates. Although lectins have been reported from …

Aberrant O-glycans expressed at the surface of cancer cells consist of membrane-tethered
glycoproteins (T and Tn antigens) and glycolipids (Lewis a, Lewis x and Forssman …

The structural features of MUC1‐like glycopeptides bearing the Tn antigen (α‐O‐GalNAc‐
Ser/Thr) in complex with an anti MUC‐1 antibody are reported at atomic resolution. For the α …

Mucin-type O-glycosylation is an important protein post-translational modification that is
abundantly expressed on cell surface proteins. Protein O-glycosylation plays a variety of …

Lectins are proteins able to bind specifically and reversibly to carbohydrates, without
promote any alteration in the covalent structure of the ligand. These proteins are found in …

Legume lectins are a diverse family of carbohydrate-binding proteins that share significant
similarities in their primary, secondary, and tertiary structures, yet exhibit remarkable …

Lectins have been used at length for basic research and clinical applications. New insights
into the molecular recognition properties enhance our basic understanding of carbohydrate …

The three-dimensional structure of Dioclea reflexa seed lectin (DrfL) was studied in detail by
a combination of X-ray crystallography, molecular docking and molecular dynamics. DrfL …

A glycosylated lectin (CTL) with specificity for mannose and glucose has been detected and
purified from seeds of Centrolobium tomentosum, a legume plant from Dalbergieae tribe. It …