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Label-free microfluidic cell sorting and detection for rapid blood analysis
Blood tests are considered as standard clinical procedures to screen for markers of diseases
and health conditions. However, the complex cellular background (> 99.9% RBCs) and …
and health conditions. However, the complex cellular background (> 99.9% RBCs) and …
Physical phenotype of blood cells is altered in COVID-19
M Kubánková, B Hohberger, J Hoffmanns, J Fürst… - Biophysical journal, 2021 - cell.com
Clinical syndrome coronavirus disease 2019 (COVID-19) induced by severe acute
respiratory syndrome coronavirus 2 is characterized by rapid spreading and high mortality …
respiratory syndrome coronavirus 2 is characterized by rapid spreading and high mortality …
Recent advances in deformation-assisted microfluidic cell sorting technologies
Cell sorting is an essential prerequisite for cell research and has great value in life science
and clinical studies. Among the many microfluidic cell sorting technologies, label-free …
and clinical studies. Among the many microfluidic cell sorting technologies, label-free …
High-throughput single-cell rheology in complex samples by dynamic real-time deformability cytometry
In life sciences, the material properties of suspended cells have attained significance close
to that of fluorescent markers but with the advantage of label-free and unbiased sample …
to that of fluorescent markers but with the advantage of label-free and unbiased sample …
Deformability-induced lift force in spiral microchannels for cell separation
Cell sorting and isolation from a heterogeneous mixture is a crucial task in many aspects of
cell biology, biotechnology and medicine. Recently, there has been an interest in methods …
cell biology, biotechnology and medicine. Recently, there has been an interest in methods …
Effects of vimentin on the migration, search efficiency, and mechanical resilience of dendritic cells
MR Shaebani, L Stankevicins, D Vesperini… - Biophysical …, 2022 - cell.com
Dendritic cells use amoeboid migration to pass through narrow passages in the extracellular
matrix and confined tissue in search for pathogens and to reach the lymph nodes and alert …
matrix and confined tissue in search for pathogens and to reach the lymph nodes and alert …
High-throughput adjustable deformability cytometry utilizing elasto-inertial focusing and virtual fluidic channel
Z Zhou, C Ni, Z Zhu, Y Chen, Z Ni, N **ang - Lab on a Chip, 2023 - pubs.rsc.org
Cell mechanical properties provide a label-free marker for indicating cell states and disease
processes. Although microfluidic deformability cytometry has demonstrated great potential …
processes. Although microfluidic deformability cytometry has demonstrated great potential …
High-throughput cell and spheroid mechanics in virtual fluidic channels
Microfluidics by soft lithography has proven to be of key importance for biophysics and life
science research. While being based on replicating structures of a master mold using …
science research. While being based on replicating structures of a master mold using …
Real-time deformability cytometry reveals sequential contraction and expansion during neutrophil priming
KR Bashant, A Vassallo, C Herold… - Journal of leukocyte …, 2019 - academic.oup.com
It has become increasingly apparent that the biomechanical properties of neutrophils impact
on their trafficking through the circulation and in particularly through the pulmonary capillary …
on their trafficking through the circulation and in particularly through the pulmonary capillary …
Cytoskeletal vimentin regulates cell size and autophagy through mTORC1 signaling
P Mohanasundaram, LS Coelho-Rato, MK Modi… - PLoS …, 2022 - journals.plos.org
The nutrient-activated mTORC1 (mechanistic target of rapamycin kinase complex 1)
signaling pathway determines cell size by controlling mRNA translation, ribosome …
signaling pathway determines cell size by controlling mRNA translation, ribosome …