[HTML][HTML] Gut microbiome and health: mechanistic insights

WM De Vos, H Tilg, M Van Hul, PD Cani - Gut, 2022 - gut.bmj.com
The gut microbiota is now considered as one of the key elements contributing to the
regulation of host health. Virtually all our body sites are colonised by microbes suggesting …

Longitudinal profiling of the microbiome at four body sites reveals core stability and individualized dynamics during health and disease

X Zhou, X Shen, JS Johnson, DJ Spakowicz… - Cell Host & Microbe, 2024 - cell.com
To understand the dynamic interplay between the human microbiome and host during
health and disease, we analyzed the microbial composition, temporal dynamics, and …

[HTML][HTML] Role of gut microbiota in the modulation of the health effects of advanced glycation end‑products

M Aschner, AV Skalny… - International …, 2023 - spandidos-publications.com
The aim of the present review was to summarize the potential interactive effects between the
gut microbiota and advanced glycation end‑product (AGE) accumulation and toxicity in the …

Protective effects of microbiome-derived inosine on lipopolysaccharide-induced acute liver damage and inflammation in mice via mediating the TLR4/NF-κB pathway

W Guo, Q **ang, B Mao, X Tang, S Cui… - Journal of Agricultural …, 2021 - ACS Publications
This research assessed the anti-inflammatory and hepatoprotective properties of inosine
and the associated mechanism. Inosine pretreatment significantly reduced the secretion of …

Identifying keystone species in microbial communities using deep learning

XW Wang, Z Sun, H Jia, S Michel-Mata… - Nature ecology & …, 2024 - nature.com
Previous studies suggested that microbial communities can harbour keystone species
whose removal can cause a dramatic shift in microbiome structure and functioning. Yet, an …

[HTML][HTML] Effects of Polygonatum sibiricum saponin on hyperglycemia, gut microbiota composition and metabolic profiles in type 2 diabetes mice

Y Chai, J Luo, Y Bao - Biomedicine & Pharmacotherapy, 2021 - Elsevier
Diabetes is a global disease that endangers human health. As reported, saponins are
effective bioactive compounds for treating type 2 diabetes mellitus (T2DM) and have …

Adverse childhood experiences and reoccurrence of illness impact the gut microbiome, which affects suicidal behaviours and the phenome of major depression …

M Maes, A Vasupanrajit, K Jirakran… - Acta …, 2023 - cambridge.org
The first publication demonstrating that major depressive disorder (MDD) is associated with
alterations in the gut microbiota appeared in 2008 (Maes et al., 2008). The purpose of the …

Modulation of chronic obstructive pulmonary disease progression by antioxidant metabolites from Pediococcus pentosaceus: enhancing gut probiotics abundance …

Y Liu, L Li, J Feng, B Wan, Q Tu, W Cai, F **… - Gut …, 2024 - Taylor & Francis
Chronic obstructive pulmonary disease (COPD), a condition primarily linked to oxidative
stress, poses significant health burdens worldwide. Recent evidence has shed light on the …

Quantification of advanced glycation end products and amino acid cross-links in foods by high-resolution mass spectrometry: Applicability of acid hydrolysis

HG Akıllıoğlu, MN Lund - Food Chemistry, 2022 - Elsevier
An analytical method was developed and validated for simultaneous identification and
quantification of advanced glycation end products (AGEs), amino acid cross-links, lysine and …

The gut microbiome responds progressively to fat and/or sugar-rich diets and is differentially modified by dietary fat and sugar

J Pessoa, GD Belew, C Barroso, C Egas, JG Jones - Nutrients, 2023 - mdpi.com
Describing diet-related effects on the gut microbiome is essential for understanding its
interactions with fat and/or sugar-rich diets to promote obesity-related metabolic diseases …