Mass spectrometry imaging for spatially resolved multi-omics molecular map**

H Zhang, KH Lu, M Ebbini, P Huang, H Lu, L Li - npj Imaging, 2024 - nature.com
The recent upswing in the integration of spatial multi-omics for conducting multidimensional
information measurements is opening a new chapter in biological research. Map** the …

Nanospray Desorption Electrospray Ionization Mass Spectrometry Imaging (nano-DESI MSI): A Tutorial Review

M Iqfath, SN Wali, S Amer, E Hernly… - ACS Measurement …, 2024 - ACS Publications
Nanospray desorption electrospray ionization (nano-DESI) is a liquid-based ambient mass
spectrometry imaging (MSI) technique that enables visualization of analyte distributions in …

MSIGen: an open-source python package for processing and visualizing mass spectrometry imaging data

E Hernly, H Hu, J Laskin - Journal of the American Society for …, 2024 - ACS Publications
Mass spectrometry imaging (MSI) provides information about the spatial localization of
molecules in complex samples with high sensitivity and molecular selectivity. Although point …

Hardware and software solutions for implementing nanospray desorption electrospray ionization (nano‐DESI) sources on commercial mass spectrometers

LX Jiang, RT Hilger, J Laskin - Journal of Mass Spectrometry, 2024 - Wiley Online Library
Nanospray desorption electrospray ionization (nano‐DESI) is an ambient ionization mass
spectrometry imaging (MSI) approach that enables spatial map** of biological and …

Development of a desorption electrospray ionization–multiple-reaction-monitoring mass spectrometry (DESI-MRM) workflow for spatially map** oxylipins in …

MJ Smith, M Nie, M Adner, J Säfholm… - Analytical …, 2024 - ACS Publications
Oxylipins are a class of low-abundance lipids formed via oxygenation of fatty acids. These
compounds include potent signaling molecules (eg, octadecanoids, eicosanoids) that can …

The Octadecanoids: Synthesis and Bioactivity of 18-Carbon Oxygenated Fatty Acids in Mammals, Bacteria, and Fungi

J Revol-Cavalier, A Quaranta, JW Newman… - Chemical …, 2024 - ACS Publications
The octadecanoids are a broad class of lipids consisting of the oxygenated products of 18-
carbon fatty acids. Originally referring to production of the phytohormone jasmonic acid, the …

Detection of IDH mutation in glioma by desorption electrospray ionization (DESI) tandem mass spectrometry

M Shahi, S Pringle, M Morris, DM Garcia… - Scientific reports, 2024 - nature.com
Desorption electrospray ionization (DESI) tandem mass spectrometry (MS) is used to assess
mutation status of isocitrate dehydrogenase (IDH) in human gliomas. Due to the diffuse …

Quantitative Analysis of Drugs in a Mimetic Tissue Model Using Nano-DESI on a Triple Quadrupole Mass Spectrometer

AM Moore, A Bowman, SN Wali… - Journal of the …, 2024 - ACS Publications
Mass spectrometry is a powerful analytical technique used at every stage of the
pharmaceutical research process. A specialized branch of this method, mass spectrometry …

An analytical evaluation of tools for lipid isomer differentiation in imaging mass spectrometry

BM Prentice - International Journal of Mass Spectrometry, 2024 - Elsevier
Imaging mass spectrometry has emerged as a powerful tool to map the spatial distributions
of lipids and metabolites in biological tissues. However, these analyses are challenged by …

Spatially resolved metabolomics: From metabolite map** to function visualising

X Min, Y Zhao, M Yu, W Zhang, X Jiang… - Clinical and …, 2024 - Wiley Online Library
Mass spectrometry imaging (MSI)‐based spatially resolved metabolomics addresses the
limitations inherent in traditional liquid chromatography‐tandem mass spectrometry (LC …