Deep learning tools for the measurement of animal behavior in neuroscience

MW Mathis, A Mathis - Current opinion in neurobiology, 2020 - Elsevier
Highlights•Deep neural networks are shattering performance benchmarks in computer
vision for various tasks.•Using modern deep learning approaches (DNNs) in the lab is a …

[HTML][HTML] Multilevel visuomotor control of locomotion in Drosophila

TL Cruz, ME Chiappe - Current Opinion in Neurobiology, 2023 - Elsevier
Vision is critical for the control of locomotion, but the underlying neural mechanisms by
which visuomotor circuits contribute to the movement of the body through space are yet not …

Ascending neurons convey behavioral state to integrative sensory and action selection brain regions

CL Chen, F Aymanns, R Minegishi, VDV Matsuda… - Nature …, 2023 - nature.com
Knowing one's own behavioral state has long been theorized as critical for contextualizing
dynamic sensory cues and identifying appropriate future behaviors. Ascending neurons …

A functionally ordered visual feature map in the Drosophila brain

NC Klapoetke, A Nern, EM Rogers, GM Rubin… - Neuron, 2022 - cell.com
Topographic maps, the systematic spatial ordering of neurons by response tuning, are
common across species. In Drosophila, the lobula columnar (LC) neuron types project from …

Global change in brain state during spontaneous and forced walk in Drosophila is composed of combined activity patterns of different neuron classes

S Aimon, KY Cheng, J Gjorgjieva, ICG Kadow - Elife, 2023 - elifesciences.org
Movement-correlated brain activity has been found across species and brain regions. Here,
we used fast whole brain lightfield imaging in adult Drosophila to investigate the relationship …

Neural circuit mechanisms underlying context-specific halting in Drosophila

N Sapkal, N Mancini, DS Kumar, N Spiller, K Murakami… - Nature, 2024 - nature.com
Walking is a complex motor programme involving coordinated and distributed activity across
the brain and the spinal cord. Halting appropriately at the correct time is a critical component …

[HTML][HTML] Synaptic gradients transform object location to action

M Dombrovski, MY Peek, JY Park, A Vaccari… - Nature, 2023 - nature.com
To survive, animals must convert sensory information into appropriate behaviours,. Vision is
a common sense for locating ethologically relevant stimuli and guiding motor responses …

Descending neuron population dynamics during odor-evoked and spontaneous limb-dependent behaviors

F Aymanns, CL Chen, P Ramdya - Elife, 2022 - elifesciences.org
Deciphering how the brain regulates motor circuits to control complex behaviors is an
important, long-standing challenge in neuroscience. In the fly, Drosophila melanogaster, this …

Fine-grained descending control of steering in walking Drosophila

HH Yang, BE Brezovec, LS Capdevila, QX Vanderbeck… - Cell, 2024 - cell.com
Locomotion involves rhythmic limb movement patterns that originate in circuits outside the
brain. Purposeful locomotion requires descending commands from the brain, but we do not …

Classification and genetic targeting of cell types in the primary taste and premotor center of the adult Drosophila brain

GR Sterne, H Otsuna, BJ Dickson, K Scott - Elife, 2021 - elifesciences.org
Neural circuits carry out complex computations that allow animals to evaluate food, select
mates, move toward attractive stimuli, and move away from threats. In insects, the …