Glycosylation of proteins is an essential process in all eukaryotes and a great diversity in
types of protein glycosylation exists in animals, plants and microorganisms. Mucin-type O …

Long noncoding RNAs (lncRNAs) have gained widespread attention in recent years as a
potentially new and crucial layer of biological regulation. lncRNAs of all kinds have been …

Abstract Background Long non-coding RNAs (lncRNAs) have a size of more than 200 bp
and are known to regulate a host of crucial cellular processes like proliferation …

We report the generation and analysis of functional data from multiple, diverse experiments
performed on a targeted 1% of the human genome as part of the pilot phase of the ENCODE …

Genomes 5 has been completely revised and updated. It is a thoroughly modern textbook
about genomes and how they are investigated. As with previous Genomes editions …

Abstract Background The Cancer Genome Atlas (TCGA) has generated comprehensive
molecular profiles. We aim to identify a set of genes whose expression patterns can …

Pseudogenes have long been labeled as “junk” DNA, failed copies of genes that arise
during the evolution of genomes. However, recent results are challenging this moniker; …

While sequencing of the human genome surprised us with how many protein-coding genes
there are, it did not fundamentally change our perspective on what a gene is. In contrast, the …

Chemosensory receptors are essential for the survival of organisms that range from bacteria
to mammals. Recent studies have shown that the numbers of functional chemosensory …

Background Pseudogenes have long been considered as nonfunctional genomic
sequences. However, recent evidence suggests that many of them might have some form of …