Semantic similarity and machine learning with ontologies

M Kulmanov, FZ Smaili, X Gao… - Briefings in …, 2021 - academic.oup.com
Ontologies have long been employed in the life sciences to formally represent and reason
over domain knowledge and they are employed in almost every major biological database …

The exercise IL-6 enigma in cancer

ST Orange, J Leslie, M Ross, DA Mann… - Trends in Endocrinology …, 2023 - cell.com
Abstract Interleukin (IL)-6 elicits both anticancer and procancer effects depending on the
context, which we have termed the 'exercise IL-6 enigma'. IL-6 is released from skeletal …

Structured prompt interrogation and recursive extraction of semantics (SPIRES): A method for populating knowledge bases using zero-shot learning

JH Caufield, H Hegde, V Emonet, NL Harris… - …, 2024 - academic.oup.com
Motivation Creating knowledge bases and ontologies is a time consuming task that relies on
manual curation. AI/NLP approaches can assist expert curators in populating these …

[HTML][HTML] The REDCap consortium: building an international community of software platform partners

PA Harris, R Taylor, BL Minor, V Elliott… - Journal of biomedical …, 2019 - Elsevier
Abstract The Research Electronic Data Capture (REDCap) data management platform was
developed in 2004 to address an institutional need at Vanderbilt University, then shared with …

OBO Foundry in 2021: operationalizing open data principles to evaluate ontologies

R Jackson, N Matentzoglu, JA Overton, R Vita… - Database, 2021 - academic.oup.com
Biological ontologies are used to organize, curate and interpret the vast quantities of data
arising from biological experiments. While this works well when using a single ontology …

WikiPathways: a multifaceted pathway database bridging metabolomics to other omics research

DN Slenter, M Kutmon, K Hanspers… - Nucleic acids …, 2018 - academic.oup.com
WikiPathways (wikipathways. org) captures the collective knowledge represented in
biological pathways. By providing a database in a curated, machine readable way, omics …

Decoupling function and taxonomy in the global ocean microbiome

S Louca, LW Parfrey, M Doebeli - Science, 2016 - science.org
Microbial metabolism powers biogeochemical cycling in Earth's ecosystems. The taxonomic
composition of microbial communities varies substantially between environments, but the …

OMA orthology in 2021: website overhaul, conserved isoforms, ancestral gene order and more

AM Altenhoff, CM Train, KJ Gilbert… - Nucleic acids …, 2021 - academic.oup.com
OMA is an established resource to elucidate evolutionary relationships among genes from
currently 2326 genomes covering all domains of life. OMA provides pairwise and groupwise …

The NHGRI GWAS Catalog, a curated resource of SNP-trait associations

D Welter, J MacArthur, J Morales, T Burdett… - Nucleic acids …, 2014 - academic.oup.com
Abstract The National Human Genome Research Institute (NHGRI) Catalog of Published
Genome-Wide Association Studies (GWAS) Catalog provides a publicly available manually …

[HTML][HTML] exRNA atlas analysis reveals distinct extracellular RNA cargo types and their carriers present across human biofluids

OD Murillo, W Thistlethwaite, J Rozowsky… - Cell, 2019 - cell.com
To develop a map of cell-cell communication mediated by extracellular RNA (exRNA), the
NIH Extracellular RNA Communication Consortium created the exRNA Atlas resource …