Our understanding of the organization of the chromatin fiber within the cell nucleus has
made great progress in the last few years. High-resolution techniques based on next …

Illuminating DNA and RNA dynamics in live cell can elucidate their life cycle and related
biochemical activities. Various protocols have been developed for labeling the regions of …

The CRISPR/dCas9 system has become an essential tool for live-cell imaging of genomic
loci, but it has limited applications in imaging low-/non-repetitive genomic loci due to the …

Inserting custom designed DNA sequences into the mammalian genome plays an essential
role in synthetic biology. In particular, the ability to introduce foreign DNA in a site-specific …

Fluorescence microscopy imaging of specific chromosomal sites is essential for genome
architecture research. To enable visualization of endogenous loci in mammalian cells …

La structure chromatinienne possède une organisation dynamique qui joue un rôle clé dans
le contrôle de la destinée cellulaire et le développement. L'accessibilité de la chromatine est …