Fluorescent dyes based on rhodamine derivatives for bioimaging and therapeutics: recent progress, challenges, and prospects

S Zeng, X Liu, YS Kafuti, H Kim, J Wang… - Chemical Society …, 2023 - pubs.rsc.org
Since their inception, rhodamine dyes have been extensively applied in biotechnology as
fluorescent markers or for the detection of biomolecules owing to their good optical physical …

[HTML][HTML] Drug-induced oxidative stress in cancer treatments: Angel or devil?

H Jiang, J Zuo, B Li, R Chen, K Luo, X **ang, S Lu… - Redox Biology, 2023 - Elsevier
Oxidative stress (OS), defined as redox imbalance in favor of oxidant burden, is one of the
most significant biological events in cancer progression. Cancer cells generally represent a …

Theranostic fluorescent probes

A Sharma, P Verwilst, M Li, D Ma, N Singh… - Chemical …, 2024 - ACS Publications
The ability to gain spatiotemporal information, and in some cases achieve spatiotemporal
control, in the context of drug delivery makes theranostic fluorescent probes an attractive …

Lutetium texaphyrin–celecoxib conjugate as a potential immuno-photodynamic therapy agent

J An, KP Lv, CV Chau, JH Lim, R Parida… - Journal of the …, 2024 - ACS Publications
Immuno-photodynamic therapy (IPDT) has emerged as a new modality for cancer treatment.
Novel photosensitizers can help achieve the promise inherent in IPDT, namely, the complete …

Bioorthogonal chemistry for prodrug activation in vivo

Q Fu, S Shen, P Sun, Z Gu, Y Bai, X Wang… - Chemical Society …, 2023 - pubs.rsc.org
Prodrugs have emerged as a major strategy for addressing clinical challenges by improving
drug pharmacokinetics, reducing toxicity, and enhancing treatment efficacy. The emergence …

Recent advances and prospects in organic molecule-based phototheranostic agents for enhanced cancer phototherapy

YY Zhao, H Kim, VN Nguyen, S Jang, WJ Jang… - Coordination Chemistry …, 2024 - Elsevier
Phototherapy, includes photodynamic therapy (PDT) and photothermal therapy (PTT), which
combine light with an adequate wavelength and a chemical phototheranostic agent in the …

Dendritic Nanomedicine with Boronate Bonds for Augmented Chemo‐Immunotherapy via Synergistic Modulation of Tumor Immune Microenvironment

Y Li, Y Wu, Z Fang, Y Zhang, H Ding, L Ren… - Advanced …, 2024 - Wiley Online Library
Unsatisfied tumor accumulation of chemotherapeutic drugs and a complicated
immunosuppressive microenvironment diminish the immune response rate and the …

Electron-Withdrawing Substituents Enhance the Type I PDT and NIR-II Fluorescence of BODIPY J Aggregates for Bioimaging and Cancer Therapy

Y Zhu, F Wu, B Zheng, Y Yang, J Yang, H **ong - Nano Letters, 2024 - ACS Publications
Organic dyes with simultaneously boosted near-infrared-II (NIR-II) fluorescence, type I
photodynamic therapy (PDT), and photothermal therapy (PTT) in the aggregate state are still …

A highly sensitive and selective near-infrared fluorescent probe for imaging peroxynitrite in living cells and drug-induced liver injury mice

X Chai, B Li, C Chen, W Zhang, L Sun… - Analytical …, 2023 - ACS Publications
Drug-induced liver injury (DILI) is a major clinical issue associated with the majority of
commercial drugs. During DILI, the peroxynitrite (ONOO–) level is upregulated in the liver …

Engineering an organic nanoplatform for augmented pyroeletroimmunotherapy

X Li, ML Gao, SS Wang, YL Li, TN Liu… - Advanced …, 2024 - Wiley Online Library
Photothermal immunotherapy has shown great promise in the treatment of tumor metastasis.
However, the thermal resistance of tumor cells substantially compromises the treatment …