The computation of genomic distances has been a very active field of computational
comparative genomics over the past 25 years. Substantial results include the polynomial …

Recurrent whole genome duplication and the ensuing loss of redundant genes—
fractionation—complicate efforts to reconstruct the gene orders and chromosomes of the …

The RACCROCHE pipeline reconstructs ancestral gene orders and chromosomal contents
of the ancestral genomes at all internal vertices of a phylogenetic tree. The strategy is to …

Given the phylogenetic relationships of several extant species, the reconstruction of their
ancestral genomes at the gene and chromosome level is made difficult by the cycles of …

This thesis presents a novel approach to reconstructing ancestral genomes of a number of
descendant species related by a phylogeny. Traditional methods face challenges due to …

Research in comparative genomics supports the investigation of important questions in
molecular biology, genetics and biomedicine. A central question in this field is the …