Doxorubicin or Adriamycin, is one of the most widely used chemotherapeutic drug for
treating a myriad of cancers. It induces cell death through multiple intracellular targets …

Polyphenols, as secondary metabolites ubiquitous in plant sources, have emerged as
pivotal bioactive compounds with far-reaching implications for human health. Plant …

Although a growing body of research has recently shown how crucial inflammation and
infection are to all major diseases, several of the medications currently available on the …

Doxorubicin (DOX) is a well-known chemotherapeutic agent extensively applied in the field
of cancer therapy. However, similar to other chemotherapeutic agents such as cisplatin …

Hepatotoxicity caused by chemotherapeutic drugs (eg, doxorubicin) is of critical concern in
cancer therapy. This study focused on investigating the modulatory effects of diosmin …

Background Liver is a vital organ responsible for metabolizing and detoxifying both
endogenous and exogenous substances in the body. However, it is susceptible to damage …

Doxorubicin is an effective anti-neoplastic agent; the reported toxicities of DOX limit its use.
Luteolin is a polyphenolic phytochemical that exhibits beneficial biological effects via …

Doxorubicin (DOX), which is frequently used in cancer treatment, has limited clinical use due
to adverse effects on healthy tissues, especially the liver. Therefore, it is necessary to …

Cancer is one of the leading causes of death worldwide, so pursuing effective and safe
therapeutics for cancer is a key research objective nowadays. Doxorubicin (DOX) is one of …

Citrus fruits are grown worldwide for their special nutritive and several health benefits.
Among citrus bioactives, naringenin, a major flavanone, exhibits a potential hepatoprotective …