Ketogenic diet for human diseases: the underlying mechanisms and potential for clinical implementations

H Zhu, D Bi, Y Zhang, C Kong, J Du, X Wu… - Signal transduction and …, 2022 - nature.com
The ketogenic diet (KD) is a high-fat, adequate-protein, and very-low-carbohydrate diet
regimen that mimics the metabolism of the fasting state to induce the production of ketone …

Astrocytes as key regulators of brain energy metabolism: new therapeutic perspectives

E Beard, S Lengacher, S Dias, PJ Magistretti… - Frontiers in …, 2022 - frontiersin.org
Astrocytes play key roles in the regulation of brain energy metabolism, which has a major
impact on brain functions, including memory, neuroprotection, resistance to oxidative stress …

[HTML][HTML] Food safety in the 21st century

F Fung, HS Wang, S Menon - Biomedical journal, 2018 - Elsevier
Food is essential to life, hence food safety is a basic human right. Billons of people in the
world are at risk of unsafe food. Many millions become sick while hundreds of thousand die …

Randomized crossover trial of a modified ketogenic diet in Alzheimer's disease

MCL Phillips, LM Deprez, GMN Mortimer… - Alzheimer's research & …, 2021 - Springer
Background Brain energy metabolism is impaired in Alzheimer's disease (AD), which may
be mitigated by a ketogenic diet. We conducted a randomized crossover trial to determine …

Sarcopenia: etiology, nutritional approaches, and miRNAs

R Cannataro, L Carbone, JL Petro, E Cione… - International journal of …, 2021 - mdpi.com
Sarcopenia, an age-related decline in skeletal muscle mass and function, dramatically
affects the quality of life. Although there is a consensus that sarcopenia is a multifactorial …

[HTML][HTML] Effect of medium chain fatty acid in human health and disease

PG Roopashree, SS Shetty, NS Kumari - Journal of Functional Foods, 2021 - Elsevier
Medium chain fatty acids (MCFAs) has unique transport system and is rapidly metabolized in
the body. It mainly occurs in coconut oil, palm kernel oil and milk products. Dietary …

[HTML][HTML] Ketogenic diet in Alzheimer's disease

M Rusek, R Pluta, M Ułamek-Kozioł… - International journal of …, 2019 - mdpi.com
At present, the prevalence of Alzheimer's disease, a devastating neurodegenerative
disorder, is increasing. Although the mechanism of the underlying pathology is not fully …

[HTML][HTML] Role of ketogenic diets in neurodegenerative diseases (Alzheimer's disease and Parkinson's disease)

D Włodarek - Nutrients, 2019 - mdpi.com
The goal of this review was to assess the effectiveness of ketogenic diets on the therapy of
neurodegenerative diseases. The ketogenic diet is a low-carbohydrate and fat-rich diet. Its …

[HTML][HTML] Effects of a medium-chain triglyceride-based ketogenic formula on cognitive function in patients with mild-to-moderate Alzheimer's disease

M Ota, J Matsuo, I Ishida, H Takano, Y Yokoi, H Hori… - Neuroscience …, 2019 - Elsevier
Clinical and animal studies suggested that a medium-chain triglyceride (MCT)-based
ketogenic diet provides an alternative energy substrate to the brain and has neuroprotective …

[HTML][HTML] Anti-oxidant and anti-inflammatory activity of ketogenic diet: new perspectives for neuroprotection in Alzheimer's disease

A Pinto, A Bonucci, E Maggi, M Corsi, R Businaro - Antioxidants, 2018 - mdpi.com
The ketogenic diet, originally developed for the treatment of epilepsy in non-responder
children, is spreading to be used in the treatment of many diseases, including Alzheimer's …