Central pattern generators in the brainstem and spinal cord: an overview of basic principles, similarities and differences

I Steuer, PA Guertin - Reviews in the Neurosciences, 2019 - degruyter.com
Central pattern generators (CPGs) are generally defined as networks of neurons capable of
enabling the production of central commands, specifically controlling stereotyped, rhythmic …

A unified hypothesis of SUDEP: Seizure‐induced respiratory depression induced by adenosine may lead to SUDEP but can be prevented by autoresuscitation and …

CL Faingold, HJ Feng - Epilepsia, 2023 - Wiley Online Library
Sudden unexpected death in epilepsy (SUDEP) is a major cause of death in people with
epilepsy (PWE). Postictal apnea leading to cardiac arrest is the most common sequence of …

[HTML][HTML] Deciphering loop gain complexity: a primer for understanding a pathophysiological trait of obstructive sleep apnea patients

C Antonaglia, GM Citton, S Soave, F Salton, B Ruaro… - Respiratory …, 2024 - Elsevier
Loop Gain (LG), a concept borrowed from engineering used to describe the stability of
electrical circuits under negative feedback, has emerged as a crucial pathophysiological trait …

Brainstem activity, apnea, and death during seizures induced by intrahippocampal kainic acid in anaesthetized rats

JGR Jefferys, MA Arafat, PP Irazoqui, TA Lovick - Epilepsia, 2019 - Wiley Online Library
Objective To investigate how prolonged seizure activity affects cardiorespiratory function
and activity of pre‐Bötzinger complex, leading to sudden death. Methods Urethane …

The role of sleep state and time of day in modulating breathing in epilepsy: implications for sudden unexpected death in epilepsy

KG Joyal, BL Kreitlow, GF Buchanan - Frontiers in neural circuits, 2022 - frontiersin.org
Sudden unexpected death in epilepsy (SUDEP) is the leading cause of death among
patients with refractory epilepsy. While the exact etiology of SUDEP is unknown, mounting …

Neuroscience and treatment of asthma, new therapeutic strategies and future aspects

F Vafaee, S Shirzad, F Shamsi, MH Boskabady - Life sciences, 2022 - Elsevier
Aims Asthma is an airway inflammatory disease that is affected by neurological and
psychological factors. The aim of present review is to investigating the relationship between …

Plasma serotonergic biomarkers are associated with hypoxemia events in preterm neonates

PM MacFarlane, RJ Martin, JM Di Fiore, TM Raffay… - Pediatric …, 2023 - nature.com
Background Hypoxemia is a physiological manifestation of immature respiratory control in
preterm neonates, which is likely impacted by neurotransmitter imbalances. We investigated …

Does volatile sedation with sevoflurane allow spontaneous breathing during prolonged prone positioning in intubated ARDS patients? A retrospective observational …

J Heider, J Bansbach, K Kaufmann, S Heinrich… - Annals of intensive …, 2019 - Springer
Background Lung-protective ventilation and prolonged prone positioning (PP) are presented
as essential in treating acute respiratory distress syndrome (ARDS). The optimal respirator …

[HTML][HTML] Respiratory neuropathology in spinocerebellar ataxia type 7

DD Biswas, Y Shi, L El Haddad, R Sethi, M Huston… - JCI …, 2024 - pmc.ncbi.nlm.nih.gov
Spinocerebellar ataxia type 7 (SCA7) is an autosomal dominant neurological disorder
caused by deleterious CAG repeat expansion in the coding region of the ataxin 7 gene …