Pre-eclampsia

E Dimitriadis, DL Rolnik, W Zhou… - Nature reviews Disease …, 2023 - nature.com
Pre-eclampsia is a life-threatening disease of pregnancy unique to humans and a leading
cause of maternal and neonatal morbidity and mortality. Women who survive pre-eclampsia …

Mechanisms of key innate immune cells in early-and late-onset preeclampsia

I Aneman, D Pienaar, S Suvakov, TP Simic… - Frontiers in …, 2020 - frontiersin.org
Preeclampsia is a complex cardiovascular disorder of pregnancy with underlying
multifactorial pathogeneses; however, its etiology is not fully understood. It is characterized …

The pathophysiological, genetic, and hormonal changes in preeclampsia: A systematic review of the molecular mechanisms

YT Chiang, KM Seow, KH Chen - International Journal of Molecular …, 2024 - mdpi.com
Preeclampsia, a serious complication of pregnancy, involves intricate molecular and cellular
mechanisms. Fetal microchimerism, where fetal cells persist within maternal tissues and in …

Hemodynamic pathways of gestational hypertension and preeclampsia

W Gyselaers - American journal of obstetrics and gynecology, 2022 - Elsevier
Gestational hypertension and preeclampsia are the 2 main types of hypertensive disorders
in pregnancy. Noninvasive maternal cardiovascular function assessment, which helps …

Host-pathogen interaction in COVID-19: Pathogenesis, potential therapeutics and vaccination strategies

PM Varghese, AG Tsolaki, H Yasmin, A Shastri… - Immunobiology, 2020 - Elsevier
The current coronavirus pandemic, COVID-19, is the third outbreak of disease caused by the
coronavirus family, after Severe Acute Respiratory Syndrome and Middle East Respiratory …

BCL6, a key oncogene, in the placenta, pre-eclampsia and endometriosis

F Louwen, NN Kreis, A Ritter, A Friemel… - Human reproduction …, 2022 - academic.oup.com
BACKGROUND The key oncogene B-cell lymphoma 6 (BCL6) drives malignant progression
by promoting proliferation, overriding DNA damage checkpoints and blocking cell terminal …

Immunological role of the maternal uterine microbiome in pregnancy: pregnancies pathologies and alterated microbiota

J Bardos, D Fiorentino, RE Longman… - Frontiers in …, 2020 - frontiersin.org
Understanding what happens at the time of embryo implantation has been the subject of
significant research. Investigators from many differing fields including maternal fetal …

Prediction and associations of preterm birth and its subtypes with eicosanoid enzymatic pathways and inflammatory markers

MT Aung, Y Yu, KK Ferguson, DE Cantonwine… - Scientific reports, 2019 - nature.com
Endogenous signaling molecules derived from lipids, peptides, and DNA, are important
regulators of physiological processes during pregnancy. The effect of their collective impact …

First trimester CD93 as a novel marker of preeclampsia and its complications: a pilot study

F Piani, G Tossetta, S Fantone, C Agostinis… - High Blood Pressure & …, 2023 - Springer
Introduction CD93 plays a crucial role in endothelial homeostasis and angiogenesis.
Recently its role in hypertension has been investigated, holding promise for novel targeted …

Exosomal microRNA-342-5p from human umbilical cord mesenchymal stem cells inhibits preeclampsia in rats

Y Chen, J **, XP Chen, J Xu, L An, H Ruan - Functional & integrative …, 2023 - Springer
We aimed to investigate the inhibitory effect of human umbilical cord mesenchymal stem cell
(hucMSC)-derived exosomes (hucMSC-Exos) transmitting microRNA-342-5p (miR-342-5p) …