Statins and cancer prevention

MF Demierre, PDR Higgins, SB Gruber, E Hawk… - Nature Reviews …, 2005 - nature.com
Randomized controlled trials for preventing cardiovascular disease indicated that statins
had provocative and unexpected benefits for reducing colorectal cancer and melanoma …

Secondary metabolites from species of the biocontrol agent Trichoderma

JL Reino, RF Guerrero, R Hernandez-Galan… - Phytochemistry …, 2008 - Springer
Trichoderma species are free-living fungi that are highly interactive in root, soil and foliar
environments and have been used successfully in field trials to control many crop …

[HTML][HTML] Statin use and reduced cancer-related mortality

SF Nielsen, BG Nordestgaard… - New England Journal of …, 2012 - Mass Medical Soc
Background A reduction in the availability of cholesterol may limit the cellular proliferation
required for cancer growth and metastasis. We tested the hypothesis that statin use begun …

[HTML][HTML] Geraniol—A review of a commercially important fragrance material

W Chen, AM Viljoen - South African Journal of Botany, 2010 - Elsevier
Geraniol is a commercially important terpene alcohol occurring in the essential oils of
several aromatic plants. It is one of the most important molecules in the flavour and …

Abrogating cholesterol esterification suppresses growth and metastasis of pancreatic cancer

J Li, D Gu, SSY Lee, B Song, S Bandyopadhyay… - Oncogene, 2016 - nature.com
Cancer cells are known to execute reprogramed metabolism of glucose, amino acids and
lipids. Here, we report a significant role of cholesterol metabolism in cancer metastasis. By …

New drugs are not enough-drug repositioning in oncology: An update

RG Armando, DLM Gomez… - … Journal of Oncology, 2020 - spandidos-publications.com
Drug repositioning refers to the concept of discovering novel clinical benefits of drugs that
are already known for use treating other diseases. The advantages of this are that several …

Effects of statins on brain tumors: a review

AR Afshari, H Mollazadeh, NC Henney… - Seminars in Cancer …, 2021 - Elsevier
Evidence from preclinical studies suggests that the competitive HMG-CoA reductase
(HMGCR) inhibitors universally known as' statins,'in addition to being powerful drugs that …

Statins and hepatotoxicity: focus on patients with fatty liver

N Chalasani - Hepatology, 2005 - journals.lww.com
Statins are among the most widely prescribed medi-cations in the western world. 1 Their
benefit in the primary and secondary prevention of cardiovascular disease is unequivocal …

Lipid-lowering drugs

K Pahan - Cellular and molecular life sciences CMLS, 2006 - Springer
Although a change in life-style is often the method of first choice for lipid lowering, lipid-
lowering drugs, in general, help to control elevated levels of different forms of lipids in …

[HTML][HTML] Vitamin D signaling and melanoma: role of vitamin D and its receptors in melanoma progression and management

AT Slominski, AA Brożyna, MA Zmijewski… - Laboratory …, 2017 - Elsevier
Ultraviolet B (UVB), in addition to having carcinogenic activity, is required for the production
of vitamin D3 (D3) in the skin which supplies> 90% of the body's requirement. Vitamin D is …