Identifying the scope and nature of memory processing by the hippocampus has proved a
formidable challenge. The major initial insights came from studies of amnesia in human …

It is often assumed that navigation implies the use, by animals, of landmarks indicating the
location of the goal. However, many animals (including humans) are able to return to the …

A model of the neuropsychology of anxiety is proposed. The model is based in the first
instance upon an analysis of the behavioural effects of the antianxiety drugs …

The ability to find one's way depends on neural algorithms that integrate information about
place, distance and direction, but the implementation of these operations in cortical …

The hippocampus is critical to remembering the flow of events in distinct experiences and, in
doing so, bridges temporal gaps between discontiguous events. Here, we report a robust …

Aging is associated with specific impairments of learning and memory, some of which are
similar to those caused by hippocampal damage. Studies of the effects of aging on …

Flexibility is a hallmark of memories that depend on the hippocampus. For navigating
animals, flexibility is necessitated by environmental changes such as blocked paths and …

Electrophysiological recording studies in the dorsocaudal region of medial entorhinal cortex
(dMEC) of the rat reveal cells whose spatial firing fields show a remarkably regular …

Hippocampal place cells are influenced by both self-motion (idiothetic) signals and external
sensory landmarks as an animal navigates its environment. To continuously update a …

There are currently two major theories about the role of the hippocampus, a distinctive
structure in the back of the temporal lobe. One says that it stores a cognitive map, the other …