Major depressive disorder (MDD) is characterized by persistent depressed mood, loss of
interest or pleasure in previously enjoyable activities, recurrent thoughts of death, and …

Depression rates in young people have risen sharply in the past decade, especially in
females, which is of concern because adolescence is a period of rapid social, emotional …

The activation of stress-related neuroendocrine systems helps to maintain homeostasis, but
excessive stress can damage body functions. We review current evidence from basic …

Adverse childhood experiences (ACEs) may leave long-lasting neurobiological scars,
increasing the risk of develo** mental disorders in later life. However, no review has …

Our understanding of the genetics of the human cerebral cortex is limited both in terms of the
diversity and the anatomical granularity of brain structural phenotypes. Here we conducted a …

Children who experience adversities have an elevated risk of mental health problems.
However, the extent to which adverse childhood experiences (ACEs) cause mental health …

The substantial phenotypic heterogeneity in autism limits our understanding of its genetic
etiology. To address this gap, here we investigated genetic differences between autistic …

Background Childhood maltreatment is associated with adverse health outcomes and this
risk can be transmitted to the next generation. We aimed to investigate the association …

Background Childhood maltreatment is associated with depression and cardiometabolic
disease in adulthood. However, the relationships with these two diseases have so far only …

Attention-deficit/hyperactivity disorder (ADHD) is a common and debilitating
neurodevelopmental disorder influenced by both genetic and environmental factors …