[HTML][HTML] Extracellular vesicle-based drug delivery systems for cancer treatment
Extracellular vesicles (EVs) are naturally occurring cell-secreted nanoparticles that play
important roles in many physiological and pathological processes. EVs enable intercellular …
important roles in many physiological and pathological processes. EVs enable intercellular …
Clinical cancer nanomedicine
J Wolfram, M Ferrari - Nano today, 2019 - Elsevier
Nanotechnology offers new solutions for the development of cancer therapeutics that display
improved efficacy and safety. Although several nanotherapeutics have received clinical …
improved efficacy and safety. Although several nanotherapeutics have received clinical …
Degradable controlled-release polymers and polymeric nanoparticles: mechanisms of controlling drug release
The development of biodegradable polymers represents a revolution in medicine spanning
over 50 years and leading to significant biotechnological advancements in drug delivery …
over 50 years and leading to significant biotechnological advancements in drug delivery …
Application of light scattering techniques to nanoparticle characterization and development
Over the years, the scientific importance of nanoparticles for biomedical applications has
increased. The high stability and biocompatibility, together with the low toxicity of the …
increased. The high stability and biocompatibility, together with the low toxicity of the …
The impact of nanoparticle protein corona on cytotoxicity, immunotoxicity and target drug delivery
In a perfect sequence of events, nanoparticles (NPs) are injected into the bloodstream
where they circulate until they reach the target tissue. The ligand on the NP surface …
where they circulate until they reach the target tissue. The ligand on the NP surface …
The importance of apparent pKa in the development of nanoparticles encapsulating siRNA and mRNA
Polymer and lipid nanoparticles have been extensively used as carriers to address the
biological barriers encountered in siRNA and mRNA delivery. We summarize the crucial role …
biological barriers encountered in siRNA and mRNA delivery. We summarize the crucial role …
Safety of nanoparticles in medicine
Nanomedicine involves the use of nanoparticles for therapeutic and diagnostic purposes.
During the past two decades, a growing number of nanomedicines have received regulatory …
During the past two decades, a growing number of nanomedicines have received regulatory …
Photodynamic therapy with nanoparticles to combat microbial infection and resistance
Infections caused by drug-resistant pathogens are rapidly increasing in incidence and pose
an urgent global health concern. New treatments are needed to address this critical situation …
an urgent global health concern. New treatments are needed to address this critical situation …
The nano-plasma interface: Implications of the protein corona
The interactions between nanoparticles and macromolecules in the blood plasma dictate the
biocompatibility and efficacy of nanotherapeutics. Accordingly, the properties of …
biocompatibility and efficacy of nanotherapeutics. Accordingly, the properties of …
Chitosan-based nanoparticles for nucleic acid delivery: technological aspects, applications, and future perspectives
Chitosan is a naturally occurring polymer derived from the deacetylation of chitin, which is
an abundant carbohydrate found mainly in the shells of various marine and terrestrial …
an abundant carbohydrate found mainly in the shells of various marine and terrestrial …