Silica‐related diseases in the modern world

RF Hoy, DC Chambers - Allergy, 2020 - Wiley Online Library
Silicosis is an ancient and potentially fatal pneumoconiosis caused by exposure to
respirable crystalline silica. Silicosis is historically a disease of miners; however, failure to …

The association between silica exposure, silicosis and tuberculosis: a systematic review and meta-analysis

R Ehrlich, P Akugizibwe, N Siegfried, D Rees - BMC public health, 2021 - Springer
Background While the association between occupational inhalation of silica dust and
pulmonary tuberculosis has been known for over a century, there has never been a …

A toxicological profile of silica nanoparticles

JY Liu, CM Sayes - Toxicology Research, 2022 - academic.oup.com
Humans are regularly exposed to silica nanoparticles in environmental and occupational
contexts, and these exposures have been implicated in the onset of adverse health effects …

Challenges and opportunities for silicosis prevention and control: need for a national health program on silicosis in India

MP Rupani - Journal of Occupational Medicine and Toxicology, 2023 - Springer
Background Silicosis has been one of the most serious occupational public health problems
worldwide for many decades. The global burden of silicosis is largely unknown, although it …

Dioscin exerts protective effects against crystalline silica-induced pulmonary fibrosis in mice

C Li, Y Lu, S Du, S Li, Y Zhang, F Liu, Y Chen… - …, 2017 - pmc.ncbi.nlm.nih.gov
Inhalation of crystalline silica particles leads to pulmonary fibrosis, eventually resulting in
respiratory failure and death. There are few effective drugs that can delay the progression of …

[HTML][HTML] Closing gaps in the tuberculosis care cascade: an action-oriented research agenda

R Subbaraman, T Jhaveri… - Journal of clinical …, 2020 - Elsevier
The care cascade—which evaluates outcomes across stages of patient engagement in a
health system—is an important framework for assessing quality of tuberculosis (TB) care. In …

[HTML][HTML] The triple burden of tuberculosis, human immunodeficiency virus and silicosis among artisanal and small-scale miners in Zimbabwe

D Moyo, R Ncube, F Kavenga, L Chikwava… - International journal of …, 2022 - mdpi.com
Artisanal and small-scale mining is characterized by an excessive exposure to silica-
containing dust, overcrowding, poor living conditions and limited access to primary health …

[HTML][HTML] Impact of respiratory dust on health: a comparison based on the toxicity of PM2. 5, silica, and nanosilica

A Hu, R Li, G Chen, S Chen - International Journal of Molecular Sciences, 2024 - mdpi.com
Respiratory dust of different particle sizes in the environment causes diverse health effects
when entering the human body and makes acute or chronic damage through multiple …

Prevalence and factors associated with tuberculosis among the mining communities in Mererani, Tanzania

AW Mbuya, IB Mboya, HH Semvua, SH Mamuya… - PLoS …, 2023 - journals.plos.org
Tuberculosis (TB) is among diseases of global health importance with Sub Saharan Africa
(SSA) accounting for 25% of the global TB burden. TB prevalence among miners in SSA is …

Tanshinone IIA attenuates silica-induced pulmonary fibrosis via Nrf2-mediated inhibition of EMT and TGF-β1/Smad signaling

F Feng, P Cheng, S Xu, N Li, H Wang, Y Zhang… - Chemico-Biological …, 2020 - Elsevier
Silicosis is an occupational pulmonary fibrosis that is caused by inhalation of silica (SiO 2),
and there are no effective drugs to treat this disease. Tanshinone IIA (Tan IIA), a natural …