Spider bite

GK Isbister, HW Fan - The Lancet, 2011 - thelancet.com
Spiders are a source of intrigue and fear, and several myths exist about their medical effects.
Many people believe that bites from various spider species cause necrotic ulceration …

Molecular diversity of spider venom

AA Vassilevski, SA Kozlov, EV Grishin - Biochemistry (Moscow), 2009 - Springer
Spider venom, a factor that has played a decisive role in the evolution of one of the most
successful groups of living organisms, is reviewed. Unique molecular diversity of venom …

A rational nomenclature for naming peptide toxins from spiders and other venomous animals

GF King, MC Gentz, P Escoubas, GM Nicholson - Toxicon, 2008 - Elsevier
Molecular toxinology research was initially driven by an interest in the small subset of animal
toxins that are lethal to humans. However, the realization that many venomous creatures …

Venom composition and strategies in spiders: is everything possible?

L Kuhn-Nentwig, R Stöcklin, W Nentwig - Advances in insect physiology, 2011 - Elsevier
This review on all spider venom components known by the end of 2010 bases on 1618
records for venom compounds from 174 spider species (= 0.41% of all known species) …

Were arachnids the first to use combinatorial peptide libraries?

BL Sollod, D Wilson, O Zhaxybayeva, JP Gogarten… - Peptides, 2005 - Elsevier
Spiders, scorpions, and cone snails are remarkable for the extent and diversity of gene-
encoded peptide neurotoxins that are expressed in their venom glands. These toxins are …

Disorders of synaptic vesicle fusion machinery

H Melland, EH Arvell, SL Gordon - Journal of neurochemistry, 2021 - Wiley Online Library
The revolution in genetic technology has ushered in a new age for our understanding of the
underlying causes of neurodevelopmental, neuromuscular and neurodegenerative …

Dangerous arachnids—Fake news or reality?

TJ Hauke, V Herzig - Toxicon, 2017 - Elsevier
The public perception of spiders and scorpions is skewed towards the potential harm they
can inflict in humans, despite recent scientific evidence that arachnid venom components …

Australian funnel-web spiders: master insecticide chemists

HW Tedford, BL Sollod, F Maggio, GF King - Toxicon, 2004 - Elsevier
Arthropods are the most diverse animal group on the planet. Their ability to inhabit a vast
array of ecological niches has inevitably brought them into conflict with humans. Although …

The peptide Phα1β, from spider venom, acts as a TRPA1 channel antagonist with antinociceptive effects in mice

R Tonello, C Fusi, S Materazzi… - British journal of …, 2017 - Wiley Online Library
Background and Purpose Peptides from venomous animals have long been important for
understanding pain mechanisms and for the discovery of pain treatments. Here, we …

Inhibition of high voltage-activated calcium channels by spider toxin PnTx3-6

LB Vieira, C Kushmerick, ME Hildebrand… - The journal of …, 2005 - Elsevier
Animal peptide toxins have become powerful tools to study structure-function relationships
and physiological roles of voltage-activated Ca 2+ channels. In the present study, we …