Signalling pathways in autism spectrum disorder: mechanisms and therapeutic implications
CC Jiang, LS Lin, S Long, XY Ke, K Fukunaga… - Signal transduction and …, 2022 - nature.com
Autism spectrum disorder (ASD) is a prevalent and complex neurodevelopmental disorder
which has strong genetic basis. Despite the rapidly rising incidence of autism, little is known …
which has strong genetic basis. Despite the rapidly rising incidence of autism, little is known …
SHANK proteins: roles at the synapse and in autism spectrum disorder
Several large-scale genomic studies have supported an association between cases of
autism spectrum disorder and mutations in the genes SH3 and multiple ankyrin repeat …
autism spectrum disorder and mutations in the genes SH3 and multiple ankyrin repeat …
Advancing the understanding of autism disease mechanisms through genetics
Progress in understanding the genetic etiology of autism spectrum disorders (ASD) has
fueled remarkable advances in our understanding of its potential neurobiological …
fueled remarkable advances in our understanding of its potential neurobiological …
From the genetic architecture to synaptic plasticity in autism spectrum disorder
T Bourgeron - Nature Reviews Neuroscience, 2015 - nature.com
Genetics studies of autism spectrum disorder (ASD) have identified several risk genes that
are key regulators of synaptic plasticity. Indeed, many of the risk genes that have been …
are key regulators of synaptic plasticity. Indeed, many of the risk genes that have been …
The neurochemistry of autism
R Marotta, MC Risoleo, G Messina, L Parisi… - Brain sciences, 2020 - mdpi.com
Autism spectrum disorder (ASD) refers to complex neurobehavioral and
neurodevelopmental conditions characterized by impaired social interaction and …
neurodevelopmental conditions characterized by impaired social interaction and …
Neurobiology of rodent self-grooming and its value for translational neuroscience
Self-grooming is a complex innate behaviour with an evolutionarily conserved sequencing
pattern and is one of the most frequently performed behavioural activities in rodents. In this …
pattern and is one of the most frequently performed behavioural activities in rodents. In this …
Sex differences in autism spectrum disorder: a review
Abstract Purpose of Review Neurodevelopmental disorders disproportionately affect males.
The mechanisms underlying male vulnerability or female protection are not known and …
The mechanisms underlying male vulnerability or female protection are not known and …
[HTML][HTML] Male sex bias in early and late onset neurodevelopmental disorders: Shared aspects and differences in Autism Spectrum Disorder, Attention Deficit …
S Santos, H Ferreira, J Martins, J Gonçalves… - Neuroscience & …, 2022 - Elsevier
Neurodevelopmental disorders are characterized by relatively early onset, with temporal
variations across conditions. These lifelong conditions lead to social and communication …
variations across conditions. These lifelong conditions lead to social and communication …
A synaptic perspective of fragile X syndrome and autism spectrum disorders
C Bagni, RS Zukin - Neuron, 2019 - cell.com
Altered synaptic structure and function is a major hallmark of fragile X syndrome (FXS),
autism spectrum disorders (ASDs), and other intellectual disabilities (IDs), which are …
autism spectrum disorders (ASDs), and other intellectual disabilities (IDs), which are …
Synaptopathology involved in autism spectrum disorder
Autism spectrum disorder (ASD) encompasses a group of multifactorial neurodevelopmental
disorders characterized by impaired social communication, social interaction and repetitive …
disorders characterized by impaired social communication, social interaction and repetitive …