A biomarker can be a substance or structure measured in body parts, fluids or products that
can affect or predict disease incidence. As age-related macular degeneration (AMD) is the …

Lineage studies conducted in the retina more than 25 years ago demonstrated the
multipotency of retinal progenitor cells (RPCs). The number and types of cells produced by …

The vast diversity of neurons and glia of the CNS is generated from a small, heterogeneous
population of progenitors that undergo transcriptional changes during development to …

The vertebrate retina is a well-characterized and tractable model for studying neurogenesis.
Retinal neurons and glia are generated in a conserved sequence from a pool of multipotent …

MicroRNAs are short regulatory RNAs that are able to post-transcriptionally modulate gene
expression and that have crucial roles in the control of physiological and pathological …

Malignant melanoma is fatal in its metastatic stage. It is therefore essential to unravel the
molecular mechanisms that govern disease progression to metastasis. MicroRNAs (miRs) …

Most regions of the vertebrate central nervous system develop by the sequential addition of
different classes of neurons and glia. This phenomenon has been best characterized in …

Background microRNAs (miRNAs) are small noncoding RNAs that regulate cognate mRNAs
at the post-transcriptional stage. Several studies have shown that miRNAs modulate gene …

Neurogenesis, the process of generating functional neurons from neural stem cells, is tightly
controlled by many intrinsic and extrinsic mechanisms. Uncovering these regulatory …

HMGA (high mobility group A)(HMGA1 and HMGA2) are small non-histone proteins that can
bind DNA and modify chromatin state, thus modulating the accessibility of regulatory factors …