Antibody positron emission tomography imaging in anticancer drug development

LE Lamberts, SP Williams… - Journal of Clinical …, 2015‏ - ascopubs.org
More than 50 monoclonal antibodies (mAbs), including several antibody–drug conjugates,
are in advanced clinical development, forming an important part of the many molecularly …

Clinical utility of DaTscan™ imaging in the evaluation of patients with parkinsonism: a US perspective

SH Isaacson, S Fisher, F Gupta… - Expert Review of …, 2017‏ - Taylor & Francis
Introduction: Single photon emission computed tomography (SPECT) with Ioflupane I123
injection (DaTscan™) was approved by the Food and Drug Administration in 2011 for striatal …

Importance of low diagnostic accuracy for early Parkinson's disease

TG Beach, CH Adler - Movement Disorders, 2018‏ - Wiley Online Library
Autopsy-validated studies of clinical diagnostic accuracy in early Parkinson's disease (PD)
indicate that, as compared with patients followed for a number of years, misdiagnosis is …

High-accuracy classification of Parkinson's disease through shape analysis and surface fitting in 123I-Ioflupane SPECT imaging

R Prashanth, SD Roy, PK Mandal… - IEEE journal of …, 2016‏ - ieeexplore.ieee.org
Early and accurate identification of Parkinsonian syndromes (PS) involving presynaptic
degeneration from nondegenerative variants such as scans without evidence of …

Artificial intelligence in the diagnosis of Parkinson's disease from ioflupane-123 single-photon emission computed tomography dopamine transporter scans using …

DH Kim, H Wit, M Thurston - Nuclear medicine communications, 2018‏ - journals.lww.com
Objective The objective of this study was to identify the extent to which artificial intelligence
could be used in the diagnosis of Parkinson's disease from ioflupane-123 (123 I) single …

Morphological characterization of functional brain imaging by isosurface analysis in Parkinson's disease

D Castillo-Barnes, FJ Martinez-Murcia… - … journal of neural …, 2020‏ - World Scientific
Finding new biomarkers to model Parkinson's Disease (PD) is a challenge not only to help
discerning between Healthy Control (HC) subjects and patients with potential PD but also as …

Early detection of Parkinson's disease using image processing and artificial neural network

M Rumman, AN Tasneem, S Farzana… - 2018 Joint 7th …, 2018‏ - ieeexplore.ieee.org
Early detection of Parkinson's disease (PD) is very crucial for effective management and
treatment of the disease. Dopaminergic images such as Single Photon Emission …

Corticobasal syndrome: neuroimaging and neurophysiological advances

F Di Stasio, A Suppa, L Marsili… - European Journal of …, 2019‏ - Wiley Online Library
Corticobasal degeneration (CBD) is a neurodegenerative condition characterized by 4R tau
protein deposition in several brain regions that clinically manifests itself as a heterogeneous …

Imaging analysis of Parkinson's disease patients using SPECT and tractography

SJ Son, M Kim, H Park - Scientific reports, 2016‏ - nature.com
Parkinson's disease (PD) is a degenerative disorder that affects the central nervous system.
PD-related alterations in structural and functional neuroimaging have not been fully …

Dopamine transporter single-photon emission computed tomography-derived radiomics signature for detecting Parkinson's disease

T Shiiba, K Takano, A Takaki, S Suwazono - EJNMMI research, 2022‏ - Springer
Background We hypothesised that the radiomics signature, which includes texture
information of dopamine transporter single-photon emission computed tomography (DAT …