Mesenchymal stem cells for regenerative medicine

Y Han, X Li, Y Zhang, Y Han, F Chang, J Ding - Cells, 2019 - mdpi.com
In recent decades, the biomedical applications of mesenchymal stem cells (MSCs) have
attracted increasing attention. MSCs are easily extracted from the bone marrow, fat, and …

Mesenchymal stem cell derived secretome and extracellular vesicles for acute lung injury and other inflammatory lung diseases

A Monsel, Y Zhu, V Gudapati, H Lim… - Expert opinion on …, 2016 - Taylor & Francis
Introduction: Acute respiratory distress syndrome is a major cause of respiratory failure in
critically ill patients. Despite extensive research into its pathophysiology, mortality remains …

Stem-cell therapy for bronchopulmonary dysplasia (BPD) in newborns

SA Omar, A Abdul-Hafez, S Ibrahim, N Pillai… - Cells, 2022 - mdpi.com
Premature newborns are at a higher risk for the development of respiratory distress
syndrome (RDS), acute lung injury (ALI) associated with lung inflammation, disruption of …

The role of lung resident mesenchymal stromal cells in the pathogenesis and repair of chronic lung disease

DF Doherty, L Roets, AD Krasnodembskaya - Stem Cells, 2023 - academic.oup.com
Mesenchymal stromal/stem cells are multipotent adult cells that can be extracted from
numerous tissues, including the lungs. Lung-resident MSCs (LR-MSCs) are localized to …

The future of bronchopulmonary dysplasia: emerging pathophysiological concepts and potential new avenues of treatment

JJP Collins, D Tibboel, IM de Kleer, IKM Reiss… - Frontiers in …, 2017 - frontiersin.org
Yearly more than 15 million babies are born premature (< 37 weeks gestational age),
accounting for more than 1 in 10 births worldwide. Lung injury caused by maternal …

[HTML][HTML] Harnessing the therapeutic potential of mesenchymal stem cell-derived exosomes in cardiac arrest: Current advances and future perspectives

K Li, Z Zhu, X Sun, L Zhao, Z Liu, J **ng - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Background Cardiac arrest (CA), characterized by sudden onset and high mortality rates, is
one of the leading causes of death globally, with a survival rate of approximately 6–24 …

A review of placenta and umbilical cord-derived stem cells and the immunomodulatory basis of their therapeutic potential in bronchopulmonary dysplasia

WK Chia, FC Cheah, NH Abdul Aziz… - Frontiers in …, 2021 - frontiersin.org
Bronchopulmonary dysplasia (BPD) is a devastating lung disorder of preterm infants as a
result of an aberrant reparative response following exposures to various antenatal and …

The characteristics and medical applications of antler stem cells

Q Liu, J Li, J Chang, Y Guo, D Wen - Stem Cell Research & Therapy, 2023 - Springer
Antlers are the only fully regenerable mammalian appendages whose annual renewal is
initiated by antler stem cells (ASCs), defined as a specialized type of mesenchymal stem …

Preventing bronchopulmonary dysplasia: new tools for an old challenge

M Álvarez-Fuente, L Moreno, JA Mitchell, IK Reiss… - Pediatric …, 2019 - nature.com
Bronchopulmonary dysplasia (BPD) is the most prevalent chronic lung disease in infants
and presents as a consequence of preterm birth. Due to the lack of effective preventive and …

[HTML][HTML] Early origins of lung disease: towards an interdisciplinary approach

NDJ Ubags, MAA Alcazar, SG Kallapur… - European …, 2020 - Eur Respiratory Soc
The prenatal and perinatal environments can have profound effects on the development of
chronic inflammatory diseases. However, mechanistic insight into how the early-life …