Abstract Elevated levels of Reactive Oxygen Species (ROS), increased antioxidant ability
and the maintenance of redox homeostasis can cumulatively contribute to tumor progression …

Wound healing requires a fine balance between the positive and deleterious effects of
reactive oxygen species (ROS); a group of extremely potent molecules, rate limiting in …

Organisms that tolerate wide variations in oxygen availability, especially to hypoxia, usually
face harsh environmental conditions during their lives. Such conditions include, for example …

By gating the traffic of molecules and cells across the vessel wall, endothelial cells play a
central role in regulating cardiovascular functions and systemic homeostasis and in …

Delayed gingival wound healing is widely observed in periodontal patients with diabetes.
However, the molecular mechanisms of the impaired function of gingival fibroblasts in …

Diabetes mellitus is a metabolic disorder that leads to the development of a number of
complications. The etiology of each diabetic complication is undoubtedly multifactorial. We …

Reactive oxygen species (ROS) are signaling molecules that influence many physiological
processes. Increased ROS bioavailability and altered redox signaling (oxidative stress) have …

This review focuses on the role of the venous valves in the genesis of thrombus formation in
venous thromboembolic disease (VTE). Clinical VTE and the evidence for the valvular origin …

Renal ischemia-reperfusion injury (IRI) can result in acute renal failure with mortality rates of
50% in severe cases. NK cells are important participants in early-stage innate immune …

Pathological angiogenesis is a key feature of many diseases including retinopathies such as
ROP (retinopathy of prematurity) and DR (diabetic retinopathy). There is considerable …